Publications by authors named "Nezdorovina V"
Results of the Third Congress on Functional and Stereotactic Neurosurgery.
Zh Vopr Neirokhir Im N N Burdenko
November 2023
After several years of waiting due to the "covid quarantine" and subsequent restrictions, we finally met. Epidemiological restrictions prevented the planned interim congress in 2021. The Third Congress on Functional and Stereotactic Neurosurgery was held in Moscow on March 15-17, 2023.
View Article and Find Full Text PDFDrug-resistance epilepsy (DRE) is a key problem in neurology. It is possible that damage to the blood-brain barrier (BBB) may affect resistance in DRE. The aim of this work was to assess the damage and dysfunction in the BBB in the area of epileptic foci in patients with DRE under conditions of neuroinflammation.
View Article and Find Full Text PDFMR morphometry in epileptology: progress and perspectives.
Zh Vopr Neirokhir Im N N Burdenko
June 2023
Article Synopsis
- - The study examines the use of morphometric MRI analysis to assess structural changes in the brain that are relevant for diagnosing epilepsy, especially in cases where traditional MRIs do not show clear abnormalities.
- - Researchers reviewed 36 publications on MRI morphometry in epilepsy from 2017 to 2022 and found that this technique can measure various brain structures, which aids in identifying the epileptogenic zone.
- - The findings suggest that MR morphometry is particularly useful in cases of MR-negative epilepsy, improving preoperative diagnosis efficiency and potentially lowering costs for patients.
A comparative analysis of two case histories showing the effects of COVID-19 and immunization with the Sputnik V vaccine on the dynamics of epilepsy is presented. The study was part of the "Epilepsy and COVID-19" research initiative in a cohort of patients with epilepsy divided into two groups: those experiencing COVID-19 and those immunized with vaccine against COVID-19. We present here a comparative analysis of two case histories: recurrence of seizures in COVID-19 in a young (male) patient and good tolerance of vaccine in an older (female) patient with comorbid pathology after surgical treatment of drug-resistant epilepsy.
View Article and Find Full Text PDFTo compare an impact of coronavirus disease and Sputnik V COVID-19 vaccine on the dynamics of epilepsy. The study is part of the ongoing «Epilepsy and COVID-19» independent research which recruited patients with epilepsy into two groups: group 1 - COVID-19 survivors and group 2 - patients vaccinated with a COVID-19 vaccine. The study compares two clinical cases: seizure recurrence with COVID-19 disease in a young patient and good tolerability of vaccination in a female elderly patient following surgical management of pharmacoresistant epilepsy with concomitant pathology.
View Article and Find Full Text PDFBackground: To study etiopathogenesis is one of the most important tasks of modern neurology. Various types of structural changes occur in drug-resistant epilepsy (DRE); however, they are described as distinct phenomena.
Objective: To provide a comprehensive characterization of structural changes in the cortex and adjacent white matter in the electrophysiological activity zone (in the epileptic focus) in patients undergoing surgery for DRE.