Genetic basis for susceptibility to noise-induced hearing loss in mice.

The C57BL/6J (B6) and DBA/2J (D2) inbred strains of mice exhibit an age-related hearing loss (AHL) due to a recessive gene (Ahl) that maps to Chromosome 10. The Ahl gene is also implicated in the susceptibility to noise-induced hearing loss (NIHL). The B6 mice (Ahl/Ahl) are more susceptible to NIHL than the CBA/CaJ (CB) mice (+(Ahl)).

The Adverse Patient Occurrences Inventory: validity, reliability, and implications.

The Adverse Patient Occurrences (APO) Inventory, a quality of care screening instrument, was tested for validity and reliability. A positive relationship was found between the relative proportion of adverse events experienced by patients with diagnoses in two diagnosis-related groups and their hospital costs and lengths of stay. As hospitals strive to provide efficient care, they will require measures such as the APO instrument to assess the quality of care they give.

Density profile of blue-sensitive cones along the horizontal meridian of macaque retina.

Intravitreal injection of some fluorescent and nonfluorescent tissue-reactive dyes results in selective intracellular staining of a specific population of cones of macaque retina that have been identified tentatively as blue-sensitive cones. This paper describes quantitative density profiles of these cones as a function of retinal eccentricity. These profiles were measured from 0 deg to about 60 deg eccentricity along the nasal and temporal segments of the horizontal meridian of macaque retina.