Commissioning of Aktina SRS cones and dosimetric validation of the RayStation photon Monte Carlo dose calculation algorithm.

Clinical implementation of SRS cones demands particular experimental care and dosimetric considerations in order to deliver precise and safe radiotherapy to patients. The purpose of this work was to present the commissioning data of recent Aktina cones combined with a 6MV flattened beam produced by an Elekta VersaHD linear accelerator. Additionally, the modelling process, and an assessment of dosimetric accuracy of the RayStation Monte Carlo dose calculation algorithm for cone based SRS was performed.

Corrigendum to: Tranexamic acid use in a patient with sickle cell disease undergoing posterior scoliosis correction surgery: safely mitigating bleeding and vaso-occlusive crises.

[This corrects the article DOI: 10.1093/jscr/rjaa559.].

Painting With Impossible Colours: Some Thoughts and Observations on Yellowish Blue.

This article considers evidence, primarily drawn from art, that one kind of impossible colour, yellowish blue, can be experienced.

Tranexamic acid use in a patient with sickle cell disease undergoing posterior scoliosis correction surgery: safely mitigating bleeding and vaso-occlusive crises.

A 15-year-old female with 2-year post-menarchal adolescent idiopathic scoliosis and sickle cell disease (SCD) underwent posterior scoliosis correction surgery. SCD is associated with higher rates of surgical complications, and these patients require careful management to prevent vaso-occlusive sickle cell crises (VOSCC); scoliosis correction surgery can be associated with high morbidity and mortality, including significant blood loss. Multiple techniques were employed to successfully prevent VOSCC in this patient including a preoperative transfusion, meticulous haemostasis at osteotomy sites, not performing a costoplasty despite presence of a rib hump, maintenance of intraoperative mean arterial pressure below 70 mmHg, aggressive postoperative hydration and the use of intraoperative tranexamic acid (TXA).

Development and commissioning of a full-size prototype fixed-beam radiotherapy system with horizontal patient rotation.

Purpose: Compared to conventional linacs with rotating gantries, a fixed-beam radiotherapy system could be smaller, more robust and more cost-effective. In this work, we developed and commissioned a prototype x-ray radiotherapy system utilizing a fixed vertical radiation beam and horizontal patient rotation.

Methods: The prototype system consists of an Elekta Synergy linac with gantry fixed at 0° and a custom-built patient rotation system (PRS).

Real-time high spatial resolution dose verification in stereotactic motion adaptive arc radiotherapy.

Purpose: Radiation treatments delivered with real-time multileaf collimator (MLC) tracking currently lack fast pretreatment or real-time quality assurance. The purpose of this study is to test a 2D silicon detector, MagicPlate-512 (MP512), in a complex clinical environment involving real-time reconfiguration of the MLC leaves during target tracking.

Methods: MP512 was placed in the center of a solid water phantom and mounted on a motion platform used to simulate three different patient motions.

A silicon strip detector array for energy verification and quality assurance in heavy ion therapy.

Purpose: The measurement of depth dose profiles for range and energy verification of heavy ion beams is an important aspect of quality assurance procedures for heavy ion therapy facilities. The steep dose gradients in the Bragg peak region of these profiles require the use of detectors with high spatial resolution. The aim of this work is to characterize a one dimensional monolithic silicon detector array called the "serial Dose Magnifying Glass" (sDMG) as an independent ion beam energy and range verification system used for quality assurance conducted for ion beams used in heavy ion therapy.

Technical Note: Angular dependence of a 2D monolithic silicon diode array for small field dosimetry.

Purpose: This study aims to investigate the 2D monolithic silicon diode array size of 52 × 52 mm (MP512) angular response. An angular correction method has been developed that improves the accuracy of dose measurement in a small field.

Methods: The MP512 was placed at the center of a cylindrical phantom, irradiated using 6 MV and 10 MV photons and incrementing the incidence of the beam angle in 15° steps from 0° to 180°, and then in 1° steps between 85° and 95°.

A 2D silicon detector array for quality assurance in small field dosimetry: DUO.

Purpose: Nowadays, there are many different applications that use small fields in radiotherapy treatments. The dosimetry of small radiation fields is not trivial due to the problems associated with lateral disequilibrium and source occlusion and requires reliable quality assurance (QA). Ideally such a QA tool should provide high spatial resolution, minimal beam perturbation and real time fast measurements.

Initial experiments with gel-water: towards MRI-linac dosimetry and imaging.

Tracking the position of a moving radiation detector in time and space during data acquisition can replicate 4D image-guided radiotherapy (4DIGRT). Magnetic resonance imaging (MRI)-linacs need MRI-visible detectors to achieve this, however, imaging solid phantoms is an issue. Hence, gel-water, a material that provides signal for MRI-visibility, and which will in future work, replace solid water for an MRI-linac 4DIGRT quality assurance tool, is discussed.

Angular independent silicon detector for dosimetry in external beam radiotherapy.

Purpose: In this work, the "edgeless" silicon detector technology is investigated, in combination with an innovative packaging solution, to manufacture silicon detectors with negligible angular response. The new diode is also characterized as a dosimeter for radiotherapy with the aim to verify its suitability as a single detector for in vivo dosimetry as well as large area 2D array that does not require angular correction to their response.

Methods: For the characterisation of the "edgeless-drop-in" detector technology, a set of samples have been manufactured with different sensitive areas (1 × 1 and 0.

MagicPlate-512: A 2D silicon detector array for quality assurance of stereotactic motion adaptive radiotherapy.

Purpose: Spatial and temporal resolutions are two of the most important features for quality assurance instrumentation of motion adaptive radiotherapy modalities. The goal of this work is to characterize the performance of the 2D high spatial resolution monolithic silicon diode array named "MagicPlate-512" for quality assurance of stereotactic body radiation therapy (SBRT) and stereotactic radiosurgery (SRS) combined with a dynamic multileaf collimator (MLC) tracking technique for motion compensation.

Methods: MagicPlate-512 is used in combination with the movable platform HexaMotion and a research version of radiofrequency tracking system Calypso driving MLC tracking software.

A two dimensional silicon detectors array for quality assurance in stereotactic radiotherapy: MagicPlate-512.

Purpose: Silicon diode arrays are commonly implemented in radiation therapy quality assurance applications as they have a number of advantages including: real time operation (compared to the film) and high spatial resolution, large dynamic range and small size (compared to ionizing chambers). Most diode arrays have detector pitch that is too coarse for routine use in small field applications. The goal of this work is to characterize the two-dimensional monolithic silicon diode array named "MagicPlate-512" (MP512) designed for QA in stereotactic body radiation therapy (SBRT) and stereotactic radio surgery (SRS).