Clinical Exome Gene Panel Analysis of a Cohort of Urothelial Bladder Cancer Patients from Sri Lanka.

Background: Bladder cancer has a high rate of recurrence and high mortality rates in those who progress to muscle invasive disease. Biomarkers and molecular sub classification of tumours beyond standard histopathology has been proposed to address therapeutic dilemmas. The Cancer Genome Atlas project and other studies have contributed to the enhanced knowledge base of the mutational landscape of urothelial bladder cancer.

A case report of post-surgical page kidney due to extensive renal hematoma following percutaneous nephrolithotomy.

Introduction And Importance: Post-surgical Page kidney due to large renal hematoma following percutaneous nephrolithotomy (PCNL) is a rare significant complication that may lead to loss of a kidney.

Case Presentation: A 50-year-old lady underwent elective left side PCNL for a 3 cm renal pelvis stone, and one week later, she presented back with a massive renal hematoma with high blood pressure.

Clinical Discussion: The ultrasound abdomen and computed tomography diagnosed a page kidney due to massive intrarenal and perirenal hematoma as a complication of PCNL.

A giant retrovesical cystic mass: A rarest of rare with a management dilemma.

A 32-year-old man investigated for subfertility and bladder outlet obstruction. He had a palpable pelvic mass and computerized tomography (CT) pelvis demonstrated that a large cystic mass (15cm) arising from right side seminal vesicle, and another small cyst from left side seminal vesicle with unilateral hydroureteronephrosis. Following a futile attempt of endoscopic drainage, mass was excised in toto via lower midline laparotomy.

Neurofibroma invading into urinary bladder presenting with symptoms of obstructed defecation and a large perineal hernia.

Background: Pelvic floor hernias pose a diagnostic and a treatment challange. Neurofibromatosis is a rare systemic disease, and urinary tract involvement is rare.

Case Presentation: Here we report a case of a 54-year-old female with multiple neurofibromatosis who presented with features of obstructed defecation and was found to have a large perineal hernia.

Giant retroperitoneal desmoid tumour.

A giant retroperitoneal desmoid (30 x 15 cm), in a 16-year old girl arising from psoas fascia is reported. Despite debulking surgery, adjuvant radiotherapy, anti-oestrogen agents and non-steroidal anti-inflammatory agents, 3 years later she died from tumour invasion of major blood vessels and bowel, leading to massive gastrointestinal bleeding.

An unusual presentation of female urethral leiomyoma.

Leiomyoma of the urethra is a rare clinical entity. We report an unusual presentation of this tumour, which led to a diagnostic and surgical dilemma. The patient was a 16-year old female who presented with a labial mass which was palpable abdominally.

Early catheter removal after transurethral resection of the prostate.

Introduction: Post-operative care of transurethral resection of the prostate (TURP) includes prolonged bladder irrigation that places a heavy burden on the nursing staff and a substantial strain on the budget. There is a trend towards early catheter removal after TURP even to the extent of performing it as a day case. We explored the feasibility and limitations of early catheter removal after TURP in our unit.