Publications by authors named "Neveen F El-Sherif"
Int J Med Mushrooms
February 2021
Article Synopsis
- Ergosterol peroxide and ganoderic acid AMI were isolated for the first time from the mycelium of the Egyptian Ganoderma resinaceum mushroom, with their structures determined through detailed NMR analysis.
- The compounds were tested for their antitumor activities on breast cancer cell lines, specifically MCF-7 and MDA-MB-231.
- Ergosterol peroxide exhibited stronger inhibition against the estrogen receptor-positive MCF-7 cells (IC50 of 1.18 μM) compared to the estrogen receptor-negative MDA-MB-231 cells (IC50 of 12.82 μM), indicating a potential targeting of estrogen receptors by this compound.*
