Efficacy of Praziquantel in the Treatment of Platynosomum fastosum in Cats with Natural Infections.

Treatments for -the liver fluke of cats-have been developed based on fecal egg counts. Post mortem fluke counts are required to understand true efficacy. In this study, two praziquantel treatment regimens were evaluated using post mortem fluke counts: a high-dose treatment (HT) of 20 mg/kg body weight (BW) administered intramuscularly (IM) once a day for three consecutive days and a low-dose treatment (LT) of 5 mg/kg BW administered once (IM) and repeated 14 days later.

Age-related periodontitis and alveolar bone loss in rice rats.

Objective: To characterize in rice rats: (a) periodontitis (PD) progress with feeding of standard laboratory rat chow (STD) during ages 4-80 weeks; and (b) PD progress with feeding of a high sucrose-casein (H-SC) diet during young adulthood.

Methods: One group (N=12) was euthanized at age 4 weeks (Baseline). Four groups (N=8-16) consumed a STD diet from baseline and were necropsied at ages 22, 30, 52, and 80 weeks.

Percutaneous Ultrasound-guided Cholecystocentesis and Bile Analysis for the Detection of Platynosomum spp.-Induced Cholangitis in Cats.

Background: Examination of bile could be useful to diagnose Platynosomum spp.-induced cholangitis in cats. Obtaining bile via percutaneous ultrasound-guided cholecystocentesis (PUC) is possible but raises safety concerns in cats with severe cholecystitis.

Testosterone dose dependently prevents bone and muscle loss in rodents after spinal cord injury.

Androgen administration protects against musculoskeletal deficits in models of sex-steroid deficiency and injury/disuse. It remains unknown, however, whether testosterone prevents bone loss accompanying spinal cord injury (SCI), a condition that results in a near universal occurrence of osteoporosis. Our primary purpose was to determine whether testosterone-enanthate (TE) attenuates hindlimb bone loss in a rodent moderate/severe contusion SCI model.