Chemically modified chitosan as a functional biomaterial for drug delivery system.

Chitosan is a natural polymer that can degrade in the environment and support green chemistry. It displays superior biocompatibility, easy access, and easy modification due to the reactive amino groups to transform or improve the physical and chemical properties. Chitosan can be chemically modified to enhance its properties, such as water solubility and biological activity.

Propranolol HCL-loaded liposomes for intranasal delivery: and evaluation of optimized formulation using design of experiments.

To develop a propranolol HCL-loaded liposomal nasal formulation for migraine prophylaxis. Formulated the liposomes through thin layer hydration method and optimized via design of experiments (DOE). The prepared liposomes were characterized for particle size, zeta potential, PDI, drug entrapment and drug loading.