Linear Codes for Hyperdimensional Computing.

Hyperdimensional computing (HDC) is an emerging computational paradigm for representing compositional information as high-dimensional vectors and has a promising potential in applications ranging from machine learning to neuromorphic computing. One of the long-standing challenges in HDC is factoring a compositional representation to its constituent factors, also known as the recovery problem. In this article, we take a novel approach to solve the recovery problem and propose the use of random linear codes.

Glioblastoma signature in the DNA of blood-derived cells.

Current approach for the detection of cancer is based on identifying genetic mutations typical to tumor cells. This approach is effective only when cancer has already emerged, however, it might be in a stage too advanced for effective treatment. Cancer is caused by the continuous accumulation of mutations; is it possible to measure the time-dependent information of mutation accumulation and predict the emergence of cancer? We hypothesize that the mutation history derived from the tandem repeat regions in blood-derived DNA carries information about the accumulation of the cancer driver mutations in other tissues.