Publications by authors named "Nestor Albinana"
COVID-19 pathophysiology is currently not fully understood, reliable prognostic factors remain elusive, and few specific therapeutic strategies have been proposed. In this scenario, availability of biomarkers is a priority. MS-based Proteomics techniques were used to profile the proteome of 81 plasma samples extracted in four consecutive days from 23 hospitalized COVID-19 associated pneumonia patients.
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- Obesity and growth hormone deficiency are common in Prader-Willi syndrome (PWS), and kisspeptin plays a role in both reproductive function and metabolism.
- The study involved 27 GH-deficient adult PWS patients, comparing their plasma kisspeptin levels before and after 12 months of GH treatment to obese and healthy subjects.
- After treatment, patients showed an increase in lean body mass, a decrease in fat mass, and a reduction in plasma kisspeptin to levels similar to healthy individuals, while BMI and leptin levels did not change.
Objective: Different adipokines have been reported to play a role in the development, progression, and severity of knee osteoarthritis, but this association may be mediated by obesity. The aim of this study was to evaluate separately the associations of leptin and adiponectin with clinical severity and inflammatory markers in nonobese and obese women with knee osteoarthritis.
Design: Cross-sectional study with systematic inclusion of 115 women with symptomatic primary knee osteoarthritis.