Publications by authors named "Nesrine Fourti"
Article Synopsis
- Psoriasis is a common autoimmune skin disease, but its exact cause is still unclear; this study explores whether specific biomarkers can indicate the presence and severity of the condition.
- The research focuses on the relationship between serum levels of VEGF, MMP-9, and TIMP-2 in 115 psoriatic patients compared to 51 controls, using ELISA methods for measurement.
- Findings show that while VEGF has low effectiveness in distinguishing between psoriasis variants, the combination of TIMP-2 and inflammation Z-score significantly improves discriminative power, highlighting the role of inflammation and tissue damage in the disease's progression.
Background: Matrix metalloproteinases (MMPs) are widely expressed in atherosclerosis lesions. The disequilibrium of MMPs driving to an overexpression or a lack of its level can be influenced by genetic variations. MMP-3 and MMP-9 may be affected by specific polymorphisms like - 1612 5 A/6A and the - 1562 C/T respectively.
View Article and Find Full Text PDFBackground: Recognizing only sharp elevation in a short period of time, the COVID-19 SARS-CoV-2 propagation is more and more marked in the whole world. Induced inflammation afterwards infection engenders a high infiltration of immune cells and cytokines that triggers matrix metalloproteinases (MMPs) activation. These endopeptidases are mediators of the lung extracellular matrix (ECM), a basic element for alveoli structure and gas exchange.
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