Publications by authors named "Nesrin Kallel"
Objectives: Several new cancer therapies targeting signaling pathways involved in the growth and progression of cancer cells were developed as personalized medicine. Our study aimed to identify epidermal growth factor receptor (EGFR) mutations for TKI treatment in non-small-cell lung cancer (NSCLC) Tunisian patients. Methods: Analysis of the TKI sensitivity mutations in exons 18 to 21 of the EGFR gene and exon 15 of the B-raf gene was performed in 79 formalin fixed-paraffin embedded (FFPE) NSCLC samples using pyrosequencing.
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- The COVID-19 pandemic has led to a variety of unusual respiratory complications, including a rare condition called spontaneous pneumomediastinum, as illustrated in a case report of a 73-year-old male patient.
- The patient presented with severe respiratory distress and was diagnosed with COVID-19 based on RT-PCR testing; his symptoms included chilling and low blood oxygen levels, leading to a diagnosis of acute respiratory distress syndrome (ARDS).
- After treatment with oxygen therapy, heparin, and dexamethasone, the patient experienced worsening symptoms on day 10, developing pneumomediastinum, but ultimately recovered without long-term lung issues, highlighting the need for healthcare professionals to recognize the various manifestations of COVID-19.