Publications by authors named "Nesma E Abdelfattah"

Genetic abnormalities provide diagnostic and prognostic information for pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) patients. The aim of this study was to determine the effects of genetic CNAs and RUNX1 gene abnormalities on the outcome of pediatric BCP-ALL patients. This study included 78 de novo-BCP-ALL pediatric patients who presented to the Pediatric Oncology Department of the National Cancer Institute (NCI), Cairo University.

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Invasive candidiasis (IC) represents a growing concern worldwide, with a considerable increase in non-albicans Candida (NAC) species. The study's primary goal was to determine if species identification by semi-nested PCR (sn-PCR) with primers for the five most prevalent Candida species is sufficient to deal with the current trends of Candida infections in cancer patients. Over one year, Candida isolates were collected from samples of patients with hematological and solid organ tumors in a single center.

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Candidemia is a life-threatening invasive fungal infection in immunocompromised patients. The widespread use of azoles and the shift toward non-albicans Candida (NAC) species remarkably increase azole resistance in developing countries. We aimed to study candidemia trends and associated risk factors in oncology patients since they vary geographically, and rapid and appropriate treatment improves outcomes.

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Synopsis of recent research by authors named "Nesma E Abdelfattah"

  • - Nesma E Abdelfattah's recent research is centered on the rising incidence of non-albicans Candida species and their implications for diagnostics and treatment in immunocompromised patients, particularly those with cancer.
  • - Her study "The impact of increasing non-albicans Candida trends on diagnostics in immunocompromised patients" explores the efficacy of semi-nested PCR for species identification amid growing trends of invasive candidiasis.
  • - In another article, Abdelfattah examines the increase of azole-resistant Candida in oncology patients, highlighting significant regional variations in candidemia trends and the critical need for rapid diagnosis and appropriate antimicrobial therapy.

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