Publications by authors named "Nesma A M Ghonimi"
Article Synopsis
- The MDS-UPDRS is a key tool for assessing Parkinson's disease, and this study aimed to validate its Arabic translation and analyze its structure compared to the English version.
- The research involved translating the scale into Arabic, conducting cognitive pretesting, and testing the new version on over 400 Arabic-speaking patients to examine its psychometric properties.
- Results showed the Arabic version matches the factor structure of the English version, confirming its validity and establishing it as an official MDS-UPDRS variant for use in Arabic-speaking populations.
Introduction Oxidative stress has been suggested to play a key role in pathogenesis of multiple sclerosis (MS), but clinical data on oxidative stress markers in MS patients and their influence on clinical and radiologic characteristics of the disease are inconsistent. The aim of this study is to assess the serum levels of malondialdehyde (MDA) as a measure of lipid peroxidation in MS patients and its relation to disease characteristics. Methods This case control study included 120 patients with clinically definite relapsing remitting multiple sclerosis (RRMS) compared to 120 age and sex -matched healthy controls.
View Article and Find Full Text PDFBackground: Oxidative stress after ischemic stroke contributes to neuronal cell injury. We tried to demonstrate an association between total antioxidant capacity (TAC) levels and outcomes after acute ischemic stroke (AIS).
Methods: We enrolled 60 patients (36 females and 24 males) who were admitted to our hospital due to AIS, in addition to 30 age and sex-matched healthy controls.
Risk of obstructive sleep apnea in multiple sclerosis: Frequency, clinical and radiological correlates.
Mult Scler Relat Disord
February 2019
Background: Primary sleep disorder, especially, obstructive sleep apnea (OSA), are noted to occur in MS patients at higher frequency than the general population.
Objectives: Our objectives are: (1) To assess the frequency of OSA risk among MS patients. (2) To evaluate the relationship between OSA risk and self-reported fatigue and sleepiness.