Investigation of hemorheological parameters in patients with major depressive disorder.

Background: Hemorheological parameters have been reported to be altered in cardiovascular disease. Major depression has been associated with increased risk of cardiovascular disease.

Objective: Our hypothesis is that hemorheological parameters are disturbed in major depressive disorder.

Comparison of endothelin and nitric oxide synthase blockers on hemorheological parameters in endotoxemic rats.

Background/aim: Septic shock is an important health problem that vastly alters cardiovascular and hemodynamic status. Increased production of nitric oxide (NO) and endothelin is a counterpart of this endotoxemic state. This study was conducted to test the hypothesis that nonselective NO synthesis blocker (L-NAME), inducible NO synthesis blocker (L-canavanine), or endothelin receptor antagonist (bosentan) will reverse the effects of sepsis on hemorheological parameters.

Acute carbon monoxide poisoning alters hemorheological parameters in human.

Acute carbon monoxide (CO) poisoning seriously hinders oxygen delivery to tissues. This harmful effect of CO may be aggravated by accompanying changes in the viscosity of blood. We had previously reported increased plasma viscosity in people chronically exposed to CO.