Characterization, biological activity, and anticancer effect of green-synthesized gold nanoparticles using Nasturtium officinale L.

Background: Nanostructured materials used have unique properties and many uses in nanotechnology. The most striking of these is using herbal compounds for the green synthesis of nanoparticles. Among the nanoparticle types used for green synthesis, gold nanoparticles (AuNPs) are used for cancer therapy due to their stable structure and non-cytotoxic.

Chitosan Nanoparticles Loaded with Quercetin and Valproic Acid: A Novel Approach for Enhancing Antioxidant Activity against Oxidative Stress in the SH-SY5Y Human Neuroblastoma Cell Line.

Background: Multiple drug-delivery systems obtained by loading nanoparticles (NPs) with different drugs that have different physicochemical properties present a promising strategy to achieve synergistic effects between drugs or overcome undesired effects. This study aims to develop a new NP by loading quercetin (Que) and valproic acid (VPA) into chitosan. In this context, our study investigated the antioxidant activities of chitosan NPs loaded with single and dual drugs containing Que against oxidative stress.

Graphene quantum dots: Synthesis, characterization, cell viability, genotoxicity for biomedical applications.

We report the synthesis and applications of a novel N-doped graphene quantum dots (GQDs) using hydrothermal reaction between citric acid and p-aminophenol. The synthesized N-doped GQDs have been characterized physico-chemically and evaluated its antioxidant, antimicrobial, DNA binding and cleavage activities. siRNA loading studies were performed and their effects on cells were evaluated.

Assessment of pollution biomarker and stable isotope data in Mytilus galloprovincialis tissues.

Superoxide dismutase (SOD) is one of the antioxidant defense enzymes in mussels and converts the superoxide anion into hydrogen peroxide and this enzyme is used as biomarkers of oxidative damage. As well as many topics in ecology, stable isotopes are also signature for organic and heavy metal pollution in aquatic ecosystems. This study aims to compare the stable carbon and nitrogen values of different mussel tissues and the changes on the SOD values of the same tissues in order to understand the relationship between two mechanisms of bioindicator processes of physiological response of mussel to pollution.

Synthesis, characterization, and evaluation of (E)-methyl 2-((2-oxonaphthalen-1(2H)-ylidene)methylamino)acetate as a biological agent and an anion sensor.

An amino acid based and bidentate Schiff base, (E)-methyl 2-((2-oxonaphthalen-1(2H)-ylidene)methylamino)acetate (ligand), was synthesized from the reaction of glycine-methyl ester hydrochloride with 2-hydroxy-1-naphthaldehyde. Characterization of the ligand was carried out using theoretical quantum-mechanical calculations and experimental spectroscopic methods. The molecular structure of the compound was confirmed using X-ray single-crystal data, NMR, FTIR and UV-Visible spectroscopy, which were in good agreement with the structure predicted by the theoretical calculations using density functional theory (DFT).

The effect of CPAP therapy on insulin-like growth factor and cognitive functions in obstructive sleep apnea patients.

Objectives: Cognitive impairment is common among patients with obstructive sleep apnea syndrome (OSAS). In this study, we aimed to investigate the effect of continuous positive airway pressure (CPAP) therapy on serum insulin-like growth factor-1 (IGF-1) levels and cognitive functions in patients with OSAS.

Patient/methods: Thirty-three patients with newly diagnosed OSAS and 17 healthy-control subjects enrolled in the study.

Chronic hepatitis B and IL28B rs12979860 polymorphism: preliminary study.

The aim of this study is to evaluate the role of IL28B rs12979860 polymorphism on pegylated interferon (peg IFN) and oral antiviral treatment in chronic hepatitis B (CHB) patients and to investigate the relationship between the severities of illness with this polymorphism. 74 CHB patients who are received treatment, 61 asymptomatic carriers and 40 healthy controls were recruited in this study. Genomic DNA of controls and patients were extracted from whole blood using High Pure PCR Template Preparation Kit (Roche, Mannheim, Germany) according to the manufacturer's instructions and stored at 4 °C.

Optimization of energy costs in the pretreatment of olive mill wastewaters by electrocoagulation.

In this study, the electrocoagulation process was evaluated as a pretreatment process for olive mill wastewaters. Aluminium (Al) and iron (Fe) electrodes, several contact times and 0.5, 1 and 2 A currents were used to compare chemical oxygen demand (COD) removal efficiencies for each case.

Methyl farnesoate controls adult male morphogenesis in the crayfish, Procambarus clarkii.

Adult male crayfish Procambarus clarkii exist in two morphotypes. They continue to molt as adults, switching between Form Is and Form IIs. Form Is are primary reproductive types, with large chelae and spines on the ischiopodites of the third and fourth pair of walking legs.