The role of platelet large cell ratio in determining mortality in COVID-19 patients.

Inflammatory mechanisms have been implicated and have been subject to research in the clinical course of COVID-19 patients. In this study, platelet large cell ratio (P-LCR) has been examined as a novel prognostic and inflammatory parameter. A total of 1992 COVID-19-positive patients admitted to COVID-19 unit of Infectious Diseases were included.

The CXCL9/10/11-CXCR3 axis as a predictor of COVID-19 progression: a prospective, case-control study.

Background: This study examined the relationship between levels of the chemokines CXCL9, CXCL10, CXCL11, and CXCR3 and mortality in patients with COVID-19..

Methods: A total of 71 patients hospitalized with COVID-19 and 35 health workers with no symptoms and negative SARS-CoV-2 PCR results were included in the study.

Evaluation of the changes in physical properties and mineral content of enamel exposed to radiation after treating with remineralization agent.

Objective: The aim of this study was to investigate the effect of different remineralization agents on the physical properties and elemental content of enamel exposed to radiation.

Material And Method: The enamel surfaces of impacted third molar teeth were prepared, and six study groups were created (n = 6). Next, 60 Gy radiation was applied to each group.

Effect of staining and bleaching on the microhardness, surface roughness and color of different composite resins.

Background: There are studies that examined the effect of staining on the surface properties of composite resins, using different solutions and bleaching applications. However, the effect of both staining and bleaching on the same composite specimens is an issue that needs to be investigated.

Objectives: The aim of this study was to investigate the surface microhardness, roughness and color changes (ΔE) of 2 different composite resins after staining and bleaching.

Colour stability of stained composite resins after brushing with whitening toothpaste.

Objective: The aim of this study was to evaluate the effect of brushing with whitening toothpaste on the colour change of composite resins discoloured with coffee.

Methods: Disc-shaped samples were prepared using one nano-hybrid (Clearfil Majesty Esthetic), one micro-hybrid (GC G-aenial Anterior) and one nano-ceramic composite (Zenit) (n = 6). After initial colour measurements, the samples were coloured in the coffee solution for 5 days.

[Specific Tests and Inflammatory Biomarkers in the Evaluation of Brucellosis Disease].

Brusellosis is the world's most common bacterial zoonotic infection and is still endemic in many developing countries. The clinical appearance of brucellosis is not specific, but the course and severity of the infection varies. In this study, it was aimed to determine the relationship between laboratory parameters and clinical response and organ involvement in patients with Brucellosis diagnosed with specific diagnostic tests.

Effects of Bisphenol A Released From Composite Fillings on Reproductive Hormone Levels in Men.

Objectives: Composite resins are the most preferred filling material because of their excellent aesthetic qualities. However, a filling material should also be biocompatible as well as aesthetic. The aim of this study was to determine the serum and saliva bisphenol-A (BPA) levels and to examine the effects of serum BPA on reproductive hormone levels after healthy men were treated with composite fillings.

Effect of fiber reinforcement on color stability of composite resins.

Aim: The aim of this study was to determine the effect of fiber reinforcement on the color changes of two different composite resins.

Materials And Methods: A silorane-based composite (Filtek Silorane, A2 shade) and a methacrylate-based composite (Valux Plus, A2 shade) were used in this study. Three groups of samples (control group with no reinforcements, polyethylene fiber [Ribbond THM]-reinforced composite, and glass fiber [everStick Net]-reinforced composite groups) were prepared from each composite ( = 8).

Technique and outcome of domino liver transplantation from patients with maple syrup urine disease: Expanding the donor pool for live donor liver transplantation.

Aim/background: Domino liver transplantation (DLT) using liver allografts from patients with metabolic disorders enhances organ utilization. Short- and long-term course and outcome of these patients can impact the decision to offer this procedure to patients, especially those with diseases that can potentially be cured with liver transplant. We reviewed the outcomes of DLT from maple syrup urine disease (MSUD) patients in our large academic pediatric and adult transplant program.

Domino liver transplantation for select metabolic disorders: Expanding the living donor pool.

Domino liver transplantation (DLT) involves transplanting liver from a patient with metabolic disease into a patient with end-stage liver disease with the expectation that the recipient will not develop the metabolic syndrome or the recurrent syndrome will have minimal affect. The domino donor gets a deceased donor or a segment of live-donor liver through the deceased donor organ allocation system. Waitlist mortality for the domino recipient exceeds morbidity associated with getting the donor disease.

The cytotoxic and oxidative effects of restorative materials in cultured human gingival fibroblasts.

The aim of this study was to evaluate the cytotoxic and oxidative effects of the most commonly used dental restorative materials on human gingival fibroblast cells (HGFCs). HGFCs were obtained from healthy individuals. The tested restorative materials were a microhybrid resin based composite, a compomer resin, a glass ionomer cement, and an amalgam alloy.

Improvements in intestine transplantation.

Transplantation of the intestine in children has presented significant challenges even as it has become a standard to treat nutritional failure due to short gut syndrome. These challenges have been addressed in part by significant improvements in short and long-term care. Noteworthy enhancements include reduced need for intestine transplantation, drug-sparing immunosuppressive regimens, immune monitoring, and improved surveillance and management of PTLD and non-adherence.

Early Treatment Was Life Saving in Varicella Pneumonia of an Immunocompetent Adult.

Chickenpox, an infection of childhood with vesicular skin rash, is caused by varicella-zoster virus (VZV). Although the infection is rare in adults, it can cause serious complications Varicella pneumonia is the most encountered complication. In this report, a VZV pneumonia case in a previously healthy adult is presented.

Pediatric Intestinal Transplantation.

Pediatric intestinal transplantation has moved from the theoretic to an actual therapy for children with irreversible intestinal failure who are suffering from complications of total parenteral nutrition. Owing to significant advancement in the management of intestinal failure and prevention of parenteral nutrition-related complications that have led to reduction in incidence of parenteral nutrition-associated liver disease and have improved intestinal adaptation, the indications for intestinal transplantation are evolving. Long-term outcomes have improved, but challenges in long-term graft function owing to chronic rejection and immunosuppressant-related complications remain the major opportunities for improvement.

Intestinal re-transplantation: indications, techniques and outcomes.

Purpose Of Review: The field of intestinal transplantation has shown significant growth and has become the gold standard therapy for patients that suffer from the complications of total parenteral nutrition due to irreversible intestinal failure. In the early years of intestinal transplant, retransplantation was associated with extremely high morbidity and mortality. The purpose of this review is to summarize recent encouraging reports, showing significant improvement in outcomes after intestinal retransplantation.

The effects of overhang amalgam restoration on levels of cytokines, gingival crevicular fluid volume and some periodontal parameters.

Purpose: To evaluate clinical periodontal findings and GCF levels of tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6) and interleukin 8 (IL-8) in patients with overhang amalgam restorations before and after overhang restoration removal.

Methods: 22 volunteer subjects (age range: 22-42 years old) with 22 overhang Class II amalgam restorations were selected. GCF samples were obtained from adjacent and contralateral teeth for IL-6, IL-8 and TNF-α measurements and analyzed using enzyme-linked immunosorbent assay (ELISA) kits.

The Effect of Polymerization and Preparation Techniques on the Microleakage of Composite Laminate Veneers.

Background: Marginal leakage is the important factor influencing the maintenance of dental esthetic.

Aim: The purpose of this study was to evaluate the relationship between the preparation techniques and type of polymerization techniques on microleakage of composite laminate veneers.

Materials And Methods: Ninety-one same sized, caries-free human maxillary central incisors were randomly assigned to 13 groups ( = 7) and were designed with four different preparation techniques (window type, feather type, bevel type, and incisal overlap type).

The effect of restorative materials on cytokines in gingival crevicular fluid.

Objective: Composition of the restorative materials may cause inflammatory responses by monocyte activation and changes in the levels of cytokine released from different cells. Interleukin-6 (IL-6), interleukin-8 (IL-8) and Tumor necrosis factor alpha (TNF-α) are important cytokine for evaluating of the inflammatory process. The aim of this study was to evaluate the different restorative materials used in class V cavities effect on gingival crevicular fluid inflammatory cytokine levels.

Clinical Variability After Partial External Biliary Diversion in Familial Intrahepatic Cholestasis 1 Deficiency.

Objectives: Familial intrahepatic cholestasis 1 (FIC1) deficiency is caused by a mutation in the ATP8B1 gene. Partial external biliary diversion (PEBD) is pursued to improve pruritus and arrest disease progression. Our aim is to describe clinical variability after PEBD in FIC1 disease.

Effects of dairy products consumption on weight loss and blood chemistry in premenopausal obese women.

Objective: To determine the effects of dairy calcium on changes in body weight and body fat mass in obese women on a weight-loss diet.

Methods: The non-randomised controlled study was conducted at Sivas Government Hospital, Turkey, between January and March 2010, and comprised obese women outpatients coming to the Nutrition and Diet Clinic. The participants were assigned to three groups according to their intake of dairy products as control, low dairy and high dairy groups.

Temperature changes caused by light curing of fiber-reinforced composite resins.

Objective: The aim of the study is to evaluate temperature change in fiber-reinforced composite (FRC) resin photopolymerized with a light-emitting diode (LED) light-curing unit (LCU).

Materials And Methods: Forty dentine disks (1 mm thick and 8 mm diameter) were prepared from human molars. The FRC specimens (2 mm thickness and 8 mm diameter) consisted of polyethylene fiber (Construct (CT)) products or glass fiber (ever Stick (ES)) and one hybrid composite bonded to the dentin disks and polymerized with an LED LCU.

Effect of water storage on the translucency of silorane-based and dimethacrylate-based composite resins with fibres.

Objectives: The purposes of this study were (1) to determine the translucency of silorane and dimethacrylate-based composite resins and (2) to evaluate the effect of water storage and reinforcement with fibre on the translucency of composite resins.

Methods: Two light-cured composite resins (A2 shade), Filtek Silorane (silorane-based composite) and Valux Plus (dimethacrylate-based composite), were used in this study. The first group was used as the control with no reinforcements, the second was reinforced with polyethylene (Ribbond THM) and the third was reinforced with a glass fibre (Everstick Net) for each composite resin.

The effects of silorane composites on levels of cytokines and periodontal parameters.

Aims: The purpose of this pilot study was to determine the effects of silorane composites on gingival crevicular fluid (GCF) levels of tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6) and IL-8, GCF volume and clinical periodontal parameters in patients with silorane composite restorations before and after restorative treatment.

Materials And Methods: A total of 20 systemically healthy non-smokers, 12 female and 8 male (age range: 24-46 years), presenting with 25 instances of primary dentine caries with subgingival margins were selected for this study. Approval was obtained from the university ethics committee and treatment plans were approved by the patients.