Khellin and visnagin in different organs of and .

and are plants that have long been used in traditional medicine. Nowadays, both herbs are commercially marketed as alternative medicines in different formulations. The main active ingredients of are known as khellin and visnagin.

Synthesis, characterization and antioxidant activity of chitosan Schiff base derivatives bearing (-)-gossypol.

In this work, two new chitosan-Schiff base derivatives (HCS-GSP and LCS-GSP) were synthesized by the condensation reaction of high molecular weight chitosan (HCS) and low molecular weight chitosan (LCS) with (-)-gossypol (GSP), respectively. For this purpose, racemic gossypol was isolated from cotton seeds and it was further enantiomerically purified by diastereomeric resolution technique using l-tryptophan methyl ester hydrochloride. Then, chitosan polymers were derivatized with (-)-gossypol by the condensation reaction.

The anticancer activity of visnagin, isolated from Ammi visnaga L., against the human malignant melanoma cell lines, HT 144.

Melanoma is a cancer of melanocyte cells and has the highest global incidence. There is a need to develop new drugs for the treatment of this deadly cancer, which is resistant to currently used treatment modalities. We investigated the anticancer activity of visnagin, a natural furanochromone derivative, isolated from Ammi visnaga L.

Synthesis, characterization and antioxidant activity of chitosan-chromone derivatives.

In this study, a new chromone-functionalized chitosan Schiff base and its cross-linked derivative were synthesized and characterized by FT-IR, UV-vis, C CP/MAS solid-state NMR, TGA, XRD-powder and SEM measurements and elemental analysis data. Degrees of substitution (DS) were determined from the elemental analysis by using the C/N ratios. The in vitro antioxidant activity of high molecular chitosan and its chromone derivatives was evaluated as radical scavengers against 1,1-diphenyl-2-picrylhydrazyl radicals (DPPH).

The chemical investigations on the ripe fruits of Ammi visnaga (Lam.) Lamarck growing in Turkey.

Two furanochromones and one furanochromone glycoside were isolated from the fruits of Ammi visnaga (L.) Lam. They were identified as khellin, visnagin, and khellol glycoside by interpretation of spectral analyses.