Characteristics and outcome of mechanically ventilated patients with 2009 H1N1 influenza in Bosnia and Herzegovina and Serbia: impact of newly established multidisciplinary intensive care units.

Aim: To describe characteristics and outcome of mechanically ventilated patients admitted to three newly established intensive care units (ICU) in Bosnia-Herzegovina and Serbia for 2009 H1N1 influenza infection.

Methods: The retrospective observational study included all mechanically ventilated adult patients of three university-affiliated hospitals between November 1, 2009 and March 1 2010 who had 2009 H1N1 influenza infection confirmed by real-time reverse transcriptase-polymerase-chain-reaction (RT-PCR) from nasopharyngeal swab specimens and respiratory secretions.

Results: The study included 50 patients, 31 male (62%), aged 43±13 years.

Importance of quick test for screening of former drug users.

Introduction: Most frequent mode of transmission of HCV today is with intravenous drug use. Former intravenous (IV) drug users present population group more exposed to HCV infection. Longer period of substance abuse, common syringe, more sexual partners (drug users) represent independent, statistically significant risk factors in this population.

Listeria meningoencephalitis in an immunocompetent person.

Listeria monocytogenes is a small, aerobic or facultative anaerobic, non-sporulating gram positive bacillus that can be isolated from soil, vegetation or animal reservoirs. There are six species of Listeria, and only L. monocytogenes is pathogenic for humans.

[Hospital sepsis and aggressive medical interventions].

Aim: To find out do the aggressive medical interventions have an effect on appearance of gram positive and gram negative hospital sepsis among 200 patients with positive clinical and laboratorial signs of sepsis and who have proved monomicrobial blood isolates.

Methods: Samples of septic patients were analyzed statistically by using x2 test and coefficient of contingency C.

Results: After we put gram negative so as gram positive sepsis to a correlation with the aggressive medical treatments, which proceeded, we got statistically significant results.

[Meningoencephalitis tuberculosis--primary isolation of resistant M. tuberculosis].

Tuberculosis is one of the main causes of serious diseases in developing countries. Despite of decreasing tuberculosis in industrial countries, diseases is not eradicated. In last fifth years the picture of diseases is changed with large number atypical cases.

[Hospital sepsis and pre-existing disease].

Aim: By retrospective study in a fifteen period from 1990 to 2004 to research if a pre-existential disease influences the appearance of gram-positive and gram-negative clear determinated hospital sepsis among 200 septic patients, selected by a random method and with clinic-laboratory signs of sepsis and monomicrobial blood culture.

Methodology: Specimen of septic patients analysed in relation to the patient condition and statistically processed using chi2 test and contigential coefficient C.

Results: We received statistically significant results when we have correlated gram-negative hospital sepsis and pre-existential disease, until this significancy was absent in gram-positive hospital sepsis.

[Analysis of amoxicillin-clavulanic acid (Xiclav) efficacy and the possibility of early switch from parenteral to oral therapy in the treatment of infections].

Early transition from parenteral to oral antibiotic therapy switch therapy play a major role in treatment because of adverse reactions of long parenteral therapy. In the prospective, comparative and randomized clinical study the efficacy of two treatment regimens were analyzed: XICLAV (amoxicillin + clavulanic acid): parenteral regiment with early transition to oral therapy and parenteral regimen in patients with bacterial infections without transition to the oral dosage form, on the other hand. In our study we've analyzed 240 hospitalized patients in the Clinic of infectious Diseases in Tuzla and Sarajevo too, so in the Institution for infectious diseases in Zenica.