Neocortical activation by electrical and chemical stimulation of the rat inferior colliculus: intra-collicular mapping and neuropharmacological characterization.

Classic experiments suggested that the midbrain reticular formation plays an important role in the induction and maintenance of high-frequency, low-amplitude activation of the electrocorticogram (ECoG). However, recent studies have shown that generalized activating systems are not restricted to the reticular formation in that non-reticular brain systems (e.g.