Publications by authors named "Nerea Nieto"
Membranes (Basel)
November 2021
Article Synopsis
- The production of reactive oxygen species (ROS) increases during cellular stress, leading to damage in lipids, proteins, and nucleic acids, with varying sensitivity across different tissues.
- Antimalarial drugs, like atovaquone and quinidine, were tested for their effects on superoxide production in human tissues, revealing significant differences in their safety profiles based on tissue type.
- The study utilized cell membrane microarrays to assess superoxide production influenced by mitochondrial activity and specific inhibitors, helping to characterize the potential oxidative toxicity of these drugs.
