Publications by authors named "Neogelia Pereira Almeida"
Endoscopic and Histopathological Findings of the Esophagus, Stomach, and Duodenum in Patients with Crohn's Disease from a Reference Center in Bahia, Brazil.
Clin Pract
June 2021
Article Synopsis
- - The study aimed to investigate endoscopic and histopathological changes in the esophagus, stomach, and duodenum of Crohn's disease patients through esophagogastroduodenoscopies and biopsies, assessing bacterial presence with Giemsa staining.
- - Out of 58 patients, significant findings included erosive esophagitis in 43.1%, gastritis in 55.2%, and erosive duodenitis in 13.8%, with varying inflammatory activity noted in patients with and without bacterial infection.
- - The findings revealed a prevalence of nonspecific changes linked to Crohn's disease, with rare instances of focally enhanced gastritis, while factors like time since diagnosis, age, and ongoing treatments
Background: The etiology of inflammatory bowel disease (IBD) is unknown, but it is believed to be multifactorial. The hygiene hypothesis proposes that better hygiene conditions would lead to less infectious disease during childhood and favor the development of immune-mediated diseases.
Aim: To test the hygiene hypothesis in IBD by assessing the environmental risk factors associated with IBD development in different regions of Brazil with diverse socioeconomic development indices.
Background: Most Crohn's disease (CD) genes discovered in recent years are associated with biological systems critical to the development of this disease. TGFB1 and IL10 are cytokines with important roles in CD. The aim of this study was to evaluate the association between CD, its clinical features and TGFB1 and IL10 gene polymorphisms.
View Article and Find Full Text PDFObjective: Inflammatory bowel disease (IBD) is a chronic disorder involving the gastrointestinal tract. Immunosuppressive drugs are usually prescribed to treat IBD patients, and this treatment can lead to tuberculosis reactivation. This paper aimed to analyze tuberculin skin test (TST) results in IBD patients at a reference center in Brazil.
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