The guidelines recommend radiofrequency ablation (RFA) for early hepatocellular carcinomas that are less than 3 cm and trans-arterial chemoembolization (TACE) for intermediate-stage tumors. Real-world patient and tumor factors commonly limit strict adherence to the guidelines. We aimed to compare the clinical outcomes for TACE and RFA in early HCC.
View Article and Find Full Text PDFIntracranial artery dissection (IAD) is an uncommon cause of cerebral ischemia. It may lead to symptoms due to rupture of subadventitial aneurysms or thromboembolism from subintimal disruption. Severe stenosis may lead to reduced cerebrovascular reserve (CVR).
View Article and Find Full Text PDFCurr Colorectal Cancer Rep
September 2018
Purpose Of Review: Colorectal cancer liver metastasis is a major clinical problem, and surgical resection is the only potentially curative treatment. We seek to discuss various liver-directed therapy modalities and explore their roles in the evolving realm of treatment strategies for metastatic colorectal cancer.
Recent Findings: Clinical outcomes for patients with colorectal cancer liver metastases have improved as more patients undergo potentially curative resection and as the armamentarium of systemic treatment and liver-directed therapies continues to expand.
Malignancies of the biliary tract include cholangiocarcinoma, gallbladder cancers and carcinoma of the ampulla of Vater. Biliary tract adenocarcinomas are the second most common primary hepatobiliary cancer. Due to their slow growing nature, non-specific and late symptomatology, these malignancies are often diagnosed in advanced stages with poor prognosis.
View Article and Find Full Text PDFAnn Acad Med Singap
September 2011
Introduction: The purpose of this retrospective study was to evaluate the short- to mid-term results of the endovascular repair of thoracic aortic disease and to present an overview of our experience with thoracic endovascular aortic repair (TEVAR) in our institution.
Materials And Methods: A retrospective review of all patients who were treated and underwent TEVAR in our institution between August 2004 and November 2009 was conducted.
Results: Technical success was achieved in 100% of the patients and the 30-day mortality rate was 0%.
Aorto-coronary artery dissection (CCAD) is rare but potentially fatal complication of catheter coronary angiography. Management is dependent on the state of distal arterial flow and the extension of retrograde aortic dissection. This manuscript describes the use and appearance of CCAD on ECG-gated multi-detector CT coronary angiogram in the acute setting.
View Article and Find Full Text PDFObjective: To determine the long-term health and development of a cohort of children in whom confined placental mosaicism (CPM) was diagnosed at prenatal diagnosis.
Methods: A retrospective cohort study was performed comparing 36 children in whom CPM had been diagnosed prenatally with 195 controls subjects in whom a normal karyotype had been detected prenatally. Data comprising birth information, health, health service utilisation, growth, development, behaviour, and the family were collected by a maternal questionnaire administered when the subjects were aged between 4 and 11 years.