Three new 3-formyl-2-arylbenzofurans from and their anti-hepatocellular carcinoma effects.

Five 3-formyl-2-arylbenzofuran derivatives, including three new compounds (-) and two known analogues (-), were identified from the 95% EtOH extract of . Extensive spectroscopic analyses were performed for the structure elucidation of all new benzofurans, and single-crystal X-ray diffraction analyses were further employed for the structure verification of iteafuranals C () and D (). In MTT assay, iteafuranal E () and iteafuranal A () displayed significant growth inhibition effect on SK-Hep-1 cells with IC values of 5.