Integrating life cycle assessment and multi criteria decision making analysis towards sustainable cocoa production system in Indonesia: An environmental, economic, and social impact perspective.

Sustainable Cocoa production practices should be investigated comprehensively to address sustainability requirements and mitigate Cocoa production issues in Indonesia. This study aims to identify the sustainable Cocoa production system considering the environmental, economic, and social impacts. Life cycle framework and multicriteria decision-making (MCDM) were integrated to obtain the study's objectives by comparing Cocoa monocropping system (CM) and Cocoa intercropping systems (IC).

Oxygen nanobubble water affects wound healing of fibroblast WI-38 cells.

This study investigated the usefulness of oxygen nanobubble water (O2NBW) for wound repair by analyzing its effect on the wound-healing process in human lung fibroblasts (WI-38 cells). The WI-38 cells were treated with 0%, 50%, and 100% O2NBW. The cell viability, reactive oxygen species (ROS) production, and wound healing following treatment were determined to elucidate the effects of O2NBW.

Gut microbial fatty acid metabolites (KetoA and KetoC) affect the progression of nonalcoholic steatohepatitis and reverse cholesterol transport metabolism in mouse model.

Nonalcoholic steatohepatitis (NASH) is a common liver disease that occurs in both alcoholics and nonalcoholics. Oxidative stress is a possible causative factor for liver diseases including NASH. Gut microorganisms, especially lactic acid bacteria, can produce unique fatty acids, including hydroxy, oxo, conjugated, and partially saturated fatty acids.