Synopsis of recent research by authors named "Neng Bao"
- Neng Bao's recent research focuses on the protective effects of various compounds against kidney-related injuries, including acute kidney injury (AKI) and renal fibrosis, emphasizing the roles of gut microbiome and specific metabolites in mediating these effects.
- Key findings include the demonstration that chrysophanol can inhibit renal fibrosis through specific signaling pathways and that cichoric acid can ameliorate sepsis-induced AKI by inhibiting macrophage polarization.
- Additionally, research highlights the potential of other compounds, such as muscone for myocardial ischemia-reperfusion injury, and emphasizes the importance of metabolic reprogramming in macrophages during septic cardiomyopathy.