Publications by authors named "Nenad Maricic"
Background: Retinoblastoma (RB) is the most common eye cancer in children that has a high mortality rate when left untreated. Mouse models for retinoblastoma have been established but are time- and cost-intensive. The aim of this work was to evaluate an orthotopic transplantation model of retinoblastoma in zebrafish that also allows for tracking migratory routes and to explore advantages and disadvantages with respect to drug testing.
View Article and Find Full Text PDFIncrease in the size of human neocortex―acquired in evolution―accounts for the unique cognitive capacity of humans. This expansion reflects the evolutionarily enhanced proliferative ability of basal progenitors (BPs), including the basal radial glia and basal intermediate progenitors (bIPs) in mammalian cortex, which may have been acquired through epigenetic alterations in BPs. However, how the epigenome in BPs differs across species is not known.
View Article and Find Full Text PDFArticle Synopsis
- There are very few human embryology collections globally, with notable ones including the Carnegie Collection, Kyoto Collection, and Blechschmidt Collection.
- The Hinrichsen Collection at Ruhr University Bochum, Germany, holds well-preserved embryos and about 16,000 histological sections.
- Digitizing this collection is crucial for its conservation and to provide access to a wide audience of researchers, with some scans available on the Digital Embryology Consortium's website.
Developmental myosin heavy chain mRNA in masseter after orthognathic surgery: a preliminary study.
J Craniomaxillofac Surg
September 2011
Introduction: A microarray study showed an increase of developmental myosin heavy chain (MyHC) mRNA in the masseter muscle after surgery. The aim of the study was to determine the expression of the embryonic MYH3 and perinatal MYH8 for use as potential marker for muscle adaptation after orthognathic surgery.
Material And Methods: 24 adult patients with a prognathic (11) or retrognathic (13) mandible were involved in the study.
MGF- and myostatin-mRNA regulation in masseter muscle after orthognathic surgery.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
October 2008
Patients with prognathism and retrognathism show extensive morphologic changes after orthognathic surgery. The inability of muscles to adapt adequately might be one reason for observed relapses. The aim of this prospective study was to analyze the regulation of functional genes after surgery and changes in myosin heavy chain (MyHC) isoform expression, a potential molecular marker profile for inadequate muscle adaptation.
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