[Beneficial effect of the ACE inhibitor captopril in normotensive patients with insulin-dependent diabetes].

The increase of glomerular filtration can often be observed in patients with insulin dependent diabetes mellitus, even in the early stage of the disease and it does not require the presence of microalbuminuria. This phenomenon can be explained by vasoconstriction occurring in the efferent arterioles. Eighteen normotensive, diabetic patients (aged: 28-42) who developed increased glomerular filtration were recruited in this study.

[Treatment possibilities for extensive pulmonary embolism as an alternative to the Trendelenburg operation].

The authors describe the clinical course of successfully treated patients with extensive, subtotal pulmonary embolism. After the diagnosis was confirmed by isotopic scan or pulmonary angiography, mechanical thrombus destruction was applied followed by low dose loco-regional thrombolysis in 11 patients by streptokinase. Five patients were treated with ultrahigh dose of streptokinase through peripheral vein, one patient via pulmonary artery catheter and one patient was treated with high dose urokinase by pulmonary catheter in combination with mechanical thrombus destruction by guide wire.

[Management of extensive, potentially fatal, pulmonary embolism].

Extensive pulmonary embolisms were suspected in 11 patients with severe cardiogenic shock admitted to an intensive care unit. The urgently established diagnosis was always based on clinical symptoms and on a complex criteria system elaborated by the authors. The "blind" diagnosis of subtotal pulmonary embolism was confirmed by further noninvasive examinations in 10 cases.

[Laryngopharyngectomy and free jejunal graft reconstruction in the treatment of hypopharyngeal tumors].

The authors performed a total laryngopharyngectomy due to a hypopharyngeal neoplasm. The continuity of the alimentary tract was restored by the insertion of a vascularized free jejunal graft, using microsurgical technique. On the occasion of this case the authors give a survey of the therapeutical methods used in the therapy of hypopharyngeal tumors, of the indications of the free jejunal transplant and of the technical issues and complications of this procedure.

[Correlations between radionuclide first passage, hemodynamic and respiratory function parameters in cor pulmonale patients].

37 patients with chronic cor pulmonale have been investigated with radionuclide first passage, microcatheter-technique, respiratory function investigation, furthermore blood gas analysis. Significant positive correlation have been found between the pulmonary circulation time and the pulmonary artery pressure; between the pulmonary mean transit time and the pulmonary artery pressure; furthermore between the pulmonary stagnation index was calculated for the characterization of peripheral pulmonary stagnation and the pulmonary artery pressure. Significant negative correlation have been found between the pulmonary circulation time, the pulmonary mean transit time and the vital capacity, the FEV1, furthermore the O2-saturation values.

Density analysis of scintigram with flow dynamics at bolus radionuclide venography: count correction with velocity.

The authors analyse the difference in the density of dynamic scintigrams produced in radionuclide venography. The difference in density is always connected with the velocity of the radionuclide flow. The lost activity is found after multiplying the count difference calculated from the time activity curve by velocity.

Testing minimal transit time in the venous system of the lower limbs using dynamic radionuclide venography.

The Authors used a test of venous occlusion applied during plethysmography in performing radionuclide venography. The minimal transit time of maximal venous outflow was tested in the subinguinal region using 99mTc-DTPA. Significant differences could be observed in compensated and non-compensated cases of occlusion of the iliac vein and chronic venous insufficiency caused by primary varicosity if compared to the controls.

Application of the parametric scan in the investigation of uteroplacental blood flow.

We developed a new radioisotope technique to measure placental blood flow for the early detection of placental insufficiency. Using the parametric scan, placental perfusion was measured in 80 late-pregnant women. The T-maximum pictures obtained made it possible to differentiate between the vascular and intervillous phases of placental blood flow.

Determination of the intervillous perfusion index in pregnancies with intrauterine growth retardation.

The authors developed a new radioisotope technique to measure placental blood flow for early detection of placental insufficiency. Using this method placental perfusion has been measured in 20 healthy pregnant women and in 15 pregnancies complicated with intrauterine growth retardation (IUGR). The T-maximum pictures obtained made it possible to differentiate between the vascular and intervillous phases of placental blood flow.

The diagnosis of hypertonic Oddi's sphincter dyskinesia.

The diagnostic possibility of hypertonic Oddi's sphincter dysfunction was evaluated in 100 cholecystectomized and 28 noncholecystectomized patients. An organic lesion interfering with free bile flow was ruled out in every case. The existence of the syndrome, i.

Disturbances of cerebrospinal fluid circulation during the acute stage of subarachnoid hemorrhage.

Radioisotope cisternography was performed and the erythrocyte and hemoglobin contents of the cerebrospinal fluid (CSF) were determined within the first 4 days after subarachnoid hemorrhage in 42 patients. The clinical condition of the patients was related to the severity of the CSF circulation disturbances. Thirty-five patients had some degree of disturbance of CSF flow, and only 2 of the 42 patients had normal flow.

[Heart-blood-pool scintigraphy in dialyzed chronic uremic patients)].

The author have carried out scintigraphic measurements of the heart in order to diagnose the presence of an exudative pericarditis 50 times in 26 dialyzed uremic patients. Within the one year's observation 13 patients had an exudative pericarditis from the beginning on. In 8 cases a regression of the exudation could be observed.