Publications by authors named "Nemanja Rilakovic"
Although the locations of promoters and enhancers have been identified in several cell types, we still have limited information on their connectivity. We developed HiCap, which combines a 4-cutter restriction enzyme Hi-C with sequence capture of promoter regions. Applying the method to mouse embryonic stem cells, we identified promoter-anchored interactions involving 15,905 promoters and 71,984 distal regions.
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- Conifers have been key players in ecosystems for over 200 million years; the genome of Norway spruce is the first complete genome for a gymnosperm.
- Despite its massive size (20 gigabases), the genome has a comparable number of genes to the much smaller Arabidopsis thaliana, indicating unique genomic features rather than whole-genome duplications.
- The research reveals shared elements across conifers, highlights specific RNA expressions, and identifies diverse genomic components, paving the way for advancements in conifer forestry and breeding.