Pseudoboehmite as a drug delivery system for acyclovir.

Herpes simplex virus is among the most prevalent sexually transmitted infections. Acyclovir is a potent, selective inhibitor of herpes viruses and it is indicated for the treatment and management of recurrent cold sores on the lips and face, genital herpes, among other diseases. The problem of the oral bioavailability of acyclovir is limited because of the low permeability across the gastrointestinal membrane.

Effect of titania addition and sintering temperature on the microstructure, optical, mechanical and biological properties of the Y-TZP/TiO composite.

Objective: The aims of this study were: 1) to evaluate the effect of sintering temperature on microstructure, density and flexural strength of a 3Y-TZP/TiO composite containing 12.5 wt% of TiO compared to 3Y-TZP specimens (control); 2) to compare 3Y-TZP with the experimental 3Y-TZP/TiO composite, both sintered at 1400 °C, with respect to the following parameters: optical properties, characteristic strength, Weibull modulus, fatigue behavior, induction of osteoblasts proliferation and differentiation (mineralization nodules formation).

Methods: The 3Y-TZP and 3Y-TZP/TiO powders were uniaxially pressed and sintered at 1200 °C, 1300 °C, 1400 °C or 1500 °C for one hour in a furnace.

Effect of ozone therapy on wound healing in the buccal mucosa of rats.

Objective: The objective of this study was to evaluate the effects of ozone therapy on wound healing formed experimentally in the oral cavity of rats.

Design: Two surgical wounds were generated on the cheeks of 24 Wistar rats, bilaterally. Half of the animals were submitted to ozone therapy on both wounds (experimental group) and the other half received no treatment (control group).

Surface interactions of a W-DLC-coated biomedical AISI 316L stainless steel in physiological solution.

The corrosion stability of a W-DLC coated surgical AISI 316L stainless steel in Hanks' solution has been evaluated. Particle induced X-ray emission (PIXE) measurements were performed to evaluate the incorporation of potentially bioactive elements from the physiological solution. The film structure was analyzed by X-ray diffractometry and micro-Raman spectroscopy.