Publications by authors named "Nelly Armanda Kala Chouakeu"
Background: The rapid spread of pyrethroid resistance has led to a change in strategy, going from pyrethroid-based nets to PBO + pyrethroid-treated nets. Although these new nets may significantly improve the control of pyrethroid-resistant mosquitoes, their durability in the field remain not yet well documented. This study investigates the durability and washing resistance of Olyset-Plus nets in the city centre and rural areas of Bertoua, Cameroon.
View Article and Find Full Text PDFBackground: Malaria remains a major public health concern in Cameroon. Understanding vector distribution and malaria transmission dynamics is of paramount importance for evaluating the performance of control strategies. This study assesses patterns of malaria transmission in four eco-epidemiological settings in Cameroon.
View Article and Find Full Text PDFDespite the contribution of secondary vectors to malaria transmission, there is still not enough information on their susceptibility status to insecticides. The present study assesses the resistance profile of to DDT. WHO tube tests were used to screen mosquito populations collected from the far-north region of Cameroon for susceptibility to 4% DDT.
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- Rapid pyrethroid resistance is a major challenge for malaria vector control in Cameroon, with insufficient data on its exact status across the country.
- The study evaluated resistance profiles through bioassays, species identification, and detection of target site mutations, finding high frequencies of the kdr L1014F allele and some occurrence of the N1575Y mutation in various regions.
- Overexpression of several detoxification genes and significant differences in cuticular hydrocarbon lipids were noted, highlighting the need for increased research and action to address insecticide resistance in malaria control strategies.
Background: To contribute to the mission of the National Malaria Control Programme (NMCP) and guide future interventions in Cameroon in general, and in Makenene in particular, this study assessed the knowledge, attitudes and practices of the population of Makenene towards the fight against malaria.
Methods: Using a semi-structured questionnaire, a descriptive cross-sectional household community survey was carried out in randomly selected households in Makenene, a locality situated between forest and savannah ecotypes.
Results: Out of the 413 households surveyed, all (100%) claimed to have heard of malaria with over 94% (n = 391) associating disease transmission with mosquito bites.
Bendiocarb and Malathion Resistance in Two Major Malaria Vector Populations in Cameroon Is Associated with High Frequency of the G119S Mutation (Ace-1) and Overexpression of Detoxification Genes.
Pathogens
July 2022
Article Synopsis
- The spread of resistance to pyrethroids in malaria-carrying mosquitoes poses a significant challenge for current malaria control strategies, highlighting a need for alternative insecticides such as carbamates and organophosphates.
- A study conducted in Cameroon evaluated the resistance levels of Anopheles gambiae mosquitoes to bendiocarb and malathion, using both bioassays and molecular techniques, and found widespread resistance except in specific locations.
- The research revealed high frequencies of the ace-1 G119S mutation and overexpression of multiple resistance-related genes, indicating that the development of resistance to these alternative insecticides could undermine future malaria control efforts.
Malaria remains a major public health problem in Cameroon. Critical steps to improve disease control include assessing human population adherence to vector control interventions, especially in areas with different cultural backgrounds. The present study seeks to assess the knowledge, attitude, and practices (KAP) of populations towards malaria prevention in four ecoepidemiological settings in Cameroon.
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