Publications by authors named "Nelli A Hovhannisyan"

The interaction of (2R, 3S)-hydroxyleucine (trypsin inhibitor) and β-hydroxyvaline with trypsin has been studied by the steady-state fluorescence spectroscopy. The analysis of fluorescence spectra has revealed the mechanism of binding of these nonprotein amino acids to trypsin. According to the docking (2R, 3S)-hydroxyleucine form hydrogen bonds with trypsin having little effect on tryptophan and tyrosine residues in enzyme molecule.

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Article Synopsis
  • Researchers analyzed ancient DNA from 44 individuals in the Near East, covering a time span of about 12,000 to 1,400 BC, from early hunter-gatherers to Bronze Age farmers.
  • They discovered that early Near Eastern populations had about half of their ancestry from a unique 'Basal Eurasian' lineage with minimal Neanderthal mixing.
  • By the Bronze Age, distinct populations from regions like the Levant and Zagros had intermingled with each other and European hunter-gatherers, leading to reduced genetic differences and significant migrations of these agricultural groups into Europe and other regions.
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