Publications by authors named "Nele-Kathrien Riffelmann"
Article Synopsis
- * In a study with mice, chronic stress made them use less energy and gain weight, even though they ate more food.
- * After the stress, their liver cells lost the ability to respond to changes in energy, and there were changes in how their DNA was organized, which might affect how their energy works in the future.
Episodes of chronic stress can result in psychic disorders like post-traumatic stress disorder, but also promote the development of metabolic syndrome and type 2 diabetes. We hypothesize that muscle, as main regulator of whole-body energy expenditure, is a central target of acute and adaptive molecular effects of stress in this context. Here, we investigate the immediate effect of a stress period on energy metabolism in Musculus gastrocnemius in our established C57BL/6 chronic variable stress (Cvs) mouse model.
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