The influence of Young's modulus of loaded implants on bone remodeling: an experimental and numerical study in the goat knee.

The aim of this study was to examine the influence of the Young's modulus of the implant material on the bone remodeling in a loaded condition. A combined animal experimental and computational study was set up. The animal experimental group comprised of 16 Saanen goats, each receiving one titanium implant (Young's modulus 110 GPa) and one high-density polyethylene (HDPE) implant (Young's modulus 1 GPa) in the left femoral condyle.

Feasibility of detecting trabecular bone around percutaneous titanium implants in rabbits by in vivo microfocus computed tomography.

Objectives: The goal of this study was to examine the feasibility of in vivo imaging of trabecular bone around titanium implants by means of microfocus computed tomography (micro-CT) and the use of rabbits for this purpose.

Materials And Methods: Ten male rabbits type Hollander, received a titanium implant (1.7 mm diameter and 10 mm length) in the trabecular bone of the left tibia.

The validation of a compression testing method for cancellous human jawbone by high-resolution finite element modeling.

Purpose: The aim of this study was to determine a reliable compression testing method for cancellous jawbone specimens and to validate it by high-resolution finite element (FE) modeling based on microcomputerized tomography (microCT) images of the specimens.

Materials And Methods: Three series of human femoral bone samples were tested to establish a compression protocol for human jawbone cores. A microCT scan of each bone sample was obtained.

Structural and radiological parameters for the characterization of jawbone.

Objectives: The aim of this study was to determine the Hounsfield values of selected bone sites on a computed tomography (CT) scan of the jaw and to investigate the relationship between this radiological parameter and structural parameters.

Materials And Methods: A selection of 24 bone samples out of eight cadaver human jaws was made. The following parameters were measured: Hounsfield value in the jaw (HU1) determined by a first CT scan, Hounsfield value of the excised bone specimen (HU2) by a second CT scan, bone mineral density (BMD) by a dual-energy X-ray absorptiometry scan, bone volume (BV/TV) by the microfocus CT scan, first peak transmission time (T(US-1)) and first zero crossing transmission time (T(US-2)) by an ultrasound measurement and Young's modulus (E(MECH)) by a compression test.

Validation of microfocus computed tomography in the evaluation of bone implant specimens.

Background: Microfocus computed tomography (muCT) is an emerging technique owing to its speed, full three-dimensional information, and nondestructive properties.

Purpose: The aim of this study was to explore the efficacy of a muCT system (Philips HOMX 161, Philips Medical Systems GmbH, Hamburg, Germany) for visualization of the bone structure around screw-type titanium implants by comparing muCT images with their histologic homologues.

Materials And Methods: Eight screw-type titanium implants were placed in the femoral condyles of two goats.