Publications by authors named "Nekkala Ramakrishna"
Article Synopsis
- The study investigates the effects of AC chemotherapy (Adriamycin and Cytoxan) on antioxidant enzymes and blood-related parameters in breast cancer patients.
- It involved 40 patients, with data collected before and after three cycles of treatment, using spectrophotometric techniques to measure enzyme levels.
- Results indicated a significant decrease in antioxidant enzymes and hematological parameters after treatment, suggesting that AC chemotherapy causes notable alterations in the body's oxidant/antioxidant balance.
Measurement of renal function is required for diagnosis and stratification of kidney disease. GFR is considered as the best overall measure of kidney function for diagnosis and treatment of patients with CKD. Measuring GFR is time consuming and hence eGFR is calculated using equations with endogenous markers like SCr.
View Article and Find Full Text PDFIt is of interest to evaluate the influence of breast cancer on oxidative stress, liver function tests, renal biomarkers, action of doxorubicin, cyclophosphamide and paclitaxel (AC-T) in the treatment and mechanism over altering the measured markers in breast cancer. Sixty histopathological confirmed cases of female patients suffering with breast carcinoma from the Department of Oncology at Omega Cancer Hospital, Visakhapatnam were included in the study. The investigation was performed in 3 groups: a control group containing 30 healthy females of similar age, 30 breast cancer patients without treatment and 30 patients receiving treatment with anticancer combination drugs AC-T.
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