Publications by authors named "Nejla Tilouche"

Article Synopsis
  • New evidence regarding the use of corticosteroids in sepsis, ARDS, and CAP led to an updated guideline aimed at improving treatment recommendations for hospitalized adults and children.
  • A diverse 22-member panel of experts, including intensivists, doctors, and nurses, followed strict conflict of interest policies to develop evidence-based clinical practice guidelines.
  • The panel reviewed five key questions and provided four recommendations, including conditional use of corticosteroids in septic shock and ARDS, a strong recommendation for severe CAP, and advised against high-dose/short-duration steroid use in septic shock.
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Scorpion envenomation is common in the tropical and subtropical regions. It poses a major public health problem with some patients having serious clinical manifestations and severe complications including death. Old World and New World scorpions are usually contrasted because of differences in venom composition, clinical presentation and severity, and, accordingly, different therapeutic approaches.

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Background: Patients with COPD are at a high risk for pulmonary embolism (PE) because of systemic inflammation and co-existing comorbidities. We aimed to determine the incidence, risk factors, and impact of PE during COPD exacerbation requiring mechanical ventilation.

Methods: This prospective cohort study was conducted between March 2013 and May 2017.

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Objectives: The best modality of administration of hydrocortisone during septic shock has been poorly evaluated and the guidelines remain unclear in this respect. This study aimed to compare bolus of hydrocortisone to a continuous infusion during septic shock.

Design: Randomized controlled, open-label trial.

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Background: The incidence and risk factors for delirium vary among studies.

Objective: We aimed to determine the incidence, risk factors, and impact on outcome of delirium in a medical Intensive Care Unit (ICU) in Tunisia using a prospective observational study.

Patients: All consecutive patients admitted to the ICU between May 2012 and April 2013 were included if they were aged more than 18 years and had an ICU stay of more than 24 h.

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To evaluate the dose-effects of Androctonus australis hector (Aah) venom injected subcutaneously on hemodynamics and neurohormonal secretions, 10 anesthetized and ventilated mongrel dogs, were split in two groups (n = 5/group). Subcutaneous injection was done with either 0.2 mg/kg or 0.

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