Publications by authors named "Neil Michel Longo-Pendy"

Article Synopsis
  • This study investigates the prevalence of protozoan parasites infecting rodents and domestic chickens in Franceville, Gabon, highlighting the risk of zoonotic diseases to humans.
  • A total of 285 animal samples were analyzed, revealing an overall prevalence of 55.8% for oocysts, significantly higher in rodents (72.4%) compared to chickens (25%).
  • The findings emphasize the need for further research to identify the specific species involved and assess their potential public health implications in the region.
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Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease with a mortality rate reaching up to 40% in humans. Currently, CCHF affects three continents: Asia, Europe, and Africa. An increase in confirmed cases in Africa has been observed since 2000.

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Article Synopsis
  • - The study analyzed malaria epidemiology in Gabon from 1980 to 2023 using five databases to track prevalence, drug resistance, and insecticide resistance markers.
  • - Gabon faces a significant public health challenge with high malaria rates, showing persistent resistance to chloroquine (CQ) and emerging resistance to sulfadoxine-pyrimethamine (SP), while artemisinin-based combination therapies (ACTs) remain effective.
  • - Recent findings indicate a high frequency of insecticide resistance markers, with alternatives like organophosphates and carbamates suggested for vector control.
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Background: This study aimed to assess the spatial distribution of Anopheles mosquito larval habitats and the environmental factors associated with them, as a prerequisite for the implementation of larviciding.

Methods: The study was conducted in December 2021, during the transition period between the end of the short rainy season (September-November) and the short dry season (December-February). Physical, biological, and land cover data were integrated with entomological observations to collect Anopheles larvae in three major towns: Mitzic, Oyem, and Bitam, using the "dipping" method during the transition from rainy to dry season.

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The Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) is still one of the main causes of death in sub-Saharan Africa. Antiretroviral therapies (ARTs) have significantly improved the health conditions of people living with HIV/AIDS (PLWHA). Consequently, a significant drop in morbidity and mortality, along with a reduced incidence of opportunistic infections (OIs), has been observed.

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In Africa, vector-borne diseases are a major public health issue, especially in cities. Urban greening is increasingly considered to promote inhabitants' well-being. However, the impact of urban green spaces on vector risk remains poorly investigated, particularly urban forests in poor hygienic conditions.

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Article Synopsis
  • Urinary tract infections (UTIs) are common in children and can lead to severe complications, particularly due to the emergence of antibiotic-resistant bacteria known as ESKAPE, which pose challenges for treatment.
  • A study conducted on 508 children in South-East Gabon found a high prevalence of UTIs (59%), primarily caused by E. coli and K. pneumoniae, with various resistance profiles complicating treatment options.
  • The research indicated that certain resistant strains, like DTR and CRE-E. coli, were linked to specific symptoms, highlighting the importance of understanding the antibiotic sensitivity of ESKAPE uropathogens for effective management of pediatric UTIs.
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Plasmodium falciparum is a parasite that causes asymptomatic or symptomatic malaria infections in humans depending on various factors. These infections are also a major cause of anemia in intertropical countries such as Gabon. Past studies have clearly demonstrated that inflammatory markers such as cytokines play a key role in the pathogenesis of malaria disease.

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The COVID-19 disease presents a large range of clinical manifestations and includes asymptomatic, mild, and severe cases. The level of severity is related to parameters associated with immunity, genetics, and biochemistry. Africa shows one of the lowest COVID-19 fatality rates but very few data on the biochemical markers of COVID-19 in patients and the factors associated with disease severity are available for the continent.

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(1) Background: Terrestrial mammals in protected areas have been identified as a potential source of antimicrobial-resistant bacteria. Studies on antimicrobial resistance in gorillas have already been conducted. Thus, this study aimed to describe the phylogroups, pathotypes and prevalence of antimicrobial resistance of isolated from western lowland gorilla's faeces living in MDNP.

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Article Synopsis
  • * A review of 7543 articles resulted in the inclusion of 42 studies spanning 91 years and identified 41 mosquito species in Gabon's diverse environments, particularly focusing on the Gambiae, Nili, Funestus, and Moucheti groups.
  • * The presence of malaria vectors in both sylvatic and urban settings indicates a complex relationship that could influence malaria transmission, highlighting the need for further entomological research to enhance vector control strategies in Gabon.
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Malaria control interventions target nocturnal feeding of the Anopheles vectors indoors to reduce parasite transmission. Mass deployment of insecticidal bed nets and indoor residual spraying with insecticides, however, may induce mosquitoes to blood-feed at places and at times when humans are not protected. These changes can set a ceiling to the efficacy of these control interventions, resulting in residual malaria transmission.

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Introduction: Discomfort in women of childbearing age associated with vaginal infections, namely bacterial vaginosis (BV), aerobic vaginitis (AV), vulvovaginal candidiasis (VVC), and trichomoniasis (TV), represent a serious and ongoing gynecological complication throughout the world.

Objective: This study aimed to investigate the etiologies of vaginal infections among outpatients in south-eastern Gabon.

Methodology: A cross-sectional study was designed using participants referred directly by their treating doctor for a vaginal swab.

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is one of the primary vectors of human malaria in sub-Saharan Africa. Recently, it has spread into the main cities of Central Africa threatening vector control programs. The adaptation of to urban environments partly results from an increased tolerance to organic pollution and insecticides.

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