Publications by authors named "Neil Khoury"
Article Synopsis
- Despite improved treatments, colorectal cancer (CRC) still has high mortality rates, but some evidence points to aspirin (ASA) potentially lowering CRC incidence and metastasis.
- A study of over 814,000 CRC patients revealed that those using ASA had significantly lower rates of total and gastrointestinal metastasis compared to non-users.
- Results showed that ASA users had better outcomes even after adjusting for factors like age and other health conditions, although more research is needed to understand how it works and how long treatment should last to be effective.
IgG4-related sclerosing cholangitis (IgG4-SC) is a unique, steroid-responsive, fibroinflammatory condition that is more commonly found in older men and is strongly associated with autoimmune pancreatitis (AIP). It may pose a diagnostic challenge at times due to closely mimicking hepatobiliary diseases such as primary sclerosing cholangitis (PSC), secondary sclerosing cholangitis (SSC), and cholangiocarcinoma. IgG4-SC has an excellent prognosis when promptly diagnosed and treated with steroids.
View Article and Find Full Text PDFArticle Synopsis
- - Disseminated histoplasmosis is a rare but serious complication that usually occurs in individuals with weakened immune systems, unlike the common, self-limiting form of the infection.
- - High-risk groups for disseminated disease include people with primary or acquired immune deficiencies, such as those with HIV/AIDS, organ transplant recipients, and individuals on immunosuppressive medications.
- - The text details an unusual case of extrapulmonary gastrointestinal histoplasmosis affecting Peyer's patches and bone marrow in a transgender woman living with HIV.
Neuropathy may arise from many different etiologies - from diabetes and nerve compression to viral infections and chemotherapy side effects; many patients suffer from neuropathic symptoms. While some etiologies produce irreversible neuropathy, others, such as vitamin and mineral deficiencies, lead to a possibly reversible disease process once treated. General clinicians should strive for early and prompt diagnosis of copper deficiency neuropathy whenever possible, especially in patients with normal vitamin B12 levels who present with a subacute gait disorder or prominent sensory ataxia.
View Article and Find Full Text PDFRacial Disparities in COVID-19 Hospitalization and In-hospital Mortality at the Height of the New York City Pandemic.
J Racial Ethn Health Disparities
October 2021
Objectives: Investigate whether or not race is associated with differences in hospitalization and survival to discharge among patients with coronavirus disease-2019 (COVID-19) at the height of the pandemic in New York City (NYC).
Methods: Single-center retrospective cohort study of COVID-19 patients hospitalized at our university-affiliated NYC hospital from 3/10/20 through 4/13/20 with follow-up to 5/1/20. Our primary endpoint was hospitalization rate among patients with confirmed COVID-19 compared with the regional population based on race.
Allergic reaction is a common clinical picture in the Emergency Department (ED). Most allergic reactions are from food or drugs. A detailed history is an integral aspect of determining the causative agent of an allergy.
View Article and Find Full Text PDFBackground: Alzheimer's disease (AD) is currently incurable and a majority of investigational drugs have failed clinical trials. One explanation for this failure may be the invalidity of hypotheses focusing on amyloid to explain AD pathogenesis. Recently, hypotheses which are centered on synaptic and metabolic dysfunction are increasingly implicated in AD.
View Article and Find Full Text PDF