Publications by authors named "Neil D Goldberg"

Article Synopsis
  • The cause of Crohn's disease (CD) is still debated, with theories suggesting it may involve an abnormal immune response to gut bacteria in people with genetic predispositions, although infections haven't been entirely dismissed.
  • There is some evidence that antibiotics can help manage the disease effectively.
  • A case report highlights a patient with CD and a severe skin condition, pyoderma gangrenosum, who experienced remission after treatment with a combination of the antibiotics rifaximin, gentamicin, and metronidazole, despite not responding to standard therapies.
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Iron deficiency anemia is the most common form of anemia worldwide, caused by poor iron intake, chronic blood loss, or impaired absorption. Patients with inflammatory bowel disease (IBD) are increasingly likely to have iron deficiency anemia, with an estimated prevalence of 36%-76%. Detection of iron deficiency is problematic as outward signs and symptoms are not always present.

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Background: Mycobacterium avium subspecies paratuberculosis (MAP) has been suspected of involvement in Crohn's disease (CD). We investigated this potential association by testing whole blood from CD patients and healthy controls for the presence of MAP by culture and molecular methods. In addition, each blood sample was analyzed for polymorphisms in the NOD2/CARD15 gene previously associated with CD.

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