Publications by authors named "Neha R Patil"

BACKGROUND Pancreatic adenocarcinoma (PDA) is associated with an 8.6-fold increased risk in Lynch syndrome patients. Here, we report the case of a Lynch syndrome PDA patient with an exceptional response to a single cycle of pembrolizumab immunotherapy.

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Article Synopsis
  • A 51-year-old woman with COVID-19 presented with severe symptoms, including fever and low oxygen levels, alongside significant laboratory abnormalities such as low hemoglobin and high D-dimer levels.
  • Imaging revealed a pulmonary embolism, but she could not receive anticoagulation due to severe anemia.
  • The case highlights how COVID-19 can trigger rare complications like cold agglutinin disease and autoimmune hemolytic anemia, necessitating awareness of these potential conditions linked to the virus.
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Background: Aminoglycoside (AG) therapy is a common cause of acute kidney injury (AKI) in cystic fibrosis (CF) patients. The aim of this study was to identify factors associated with AKI during intravenous AG courses in this population.

Methods: This was a matched case-control study utilizing two independent cohorts of hospitalized CF patients receiving ≥ 3 days of intravenous AG at Cincinnati Children's Hospital Medical Center and Children's of Alabama.

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Background: Acute kidney injury (AKI) impairs electrolyte balance, alters fluid homeostasis and decreases toxin excretion. More recent data suggest it also affects the physiology of distant organs.

Methods: We performed a prospective cohort study which invloved 122 premature infants [birth weight (BW) ≤1200 g and/or gestational age (GA) <31 weeks] to determine relationships between AKI and bronchopulmonary dysplasia (BPD)/mortality.

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