- Connective tissue disorders (CTDs) are a growing group of autoimmune diseases, particularly prevalent in India, with Systemic Lupus Erythematosus (SLE) most common, especially impacting women.
- The study aimed to assess the effectiveness of the Indirect Immunofluorescence Assay (IFA) for screening ANA in CTDs and to analyze the different patterns and titres of ANA positive samples.
- Results indicated that out of 57 samples tested, 36.8% were ANA positive, predominantly in perimenopausal women, with Speckled being the most common pattern; IFA showed comparable sensitivity and specificity to ELISA, making it a useful and cost-effective screening method for