Publications by authors named "Neha Kashyap"
Article Synopsis
- - The Foot Function Index (FFI) is a standardized tool assessing the effects of foot problems on daily activities, and a Hindi version (FFI-Hi) was developed to address the needs of the 571 million Hindi speakers worldwide facing foot issues.
- - The study involved translating and adapting the FFI into Hindi, followed by testing its reliability and validity with 223 participants, primarily males with an average age of 47, most suffering from plantar fasciopathy.
- - The results showed that the FFI-Hi has good internal consistency and excellent reproducibility, making it a reliable tool for clinical and research purposes in Hindi-speaking populations.
Article Synopsis
- The study investigates the role of solute carrier family transporters (SLCs) in the placenta, linking their dysregulation to pregnancy disorders like preeclampsia (PE) and intrauterine growth restriction (IUGR).
- Researchers conducted a meta-analysis of public data and verified findings through qPCR, focusing on differentially expressed SLCs in PE and IUGR samples.
- The results showed significant downregulation of specific SLCs (SLC6A8, SLC16A10, SLC25A3, SLC29A3) in affected placental samples, suggesting their potential role in the pathogenesis of these pregnancy complications.
Treatment-seeking behavior (TSB) in relation to dengue infection is a critical aspect of public health, and understanding the factors that influence it is crucial for effective disease management. This research delves into key determinants of dengue TSB by examining the perceptions and behaviors of individuals in Costa Rica, in relation to the Health Belief Model (HBM). This study utilized naturalistic inquiry and incorporated a qualitative research design involving nine students organized into four teams, with at least one student on each team with high Spanish fluency.
View Article and Find Full Text PDFBackground: In 2020, 203 million people experienced neck pain, with a higher prevalence in women. By 2050, it is predicted that neck pain will affect 269 million people, representing a 32.5% increase.
View Article and Find Full Text PDFBackground: Nurse led noncommunicable diseases (NCD) clinic may address the significant shortage of human resource for health for managing common NCDs. The objective of this study is to assess the feasibility and effectiveness of nurse-led NCD clinic for identification, prevention, and management of common NCDs.
Materials And Methods: A quasi experimental study was conducted at a Public Health Dispensary in periurban community of Northern India.
Article Synopsis
- Hypertensive disorders of pregnancy (HDP) affect 5%-10% of pregnancies globally, with four main types identified, including preeclampsia (PE), which significantly contributes to maternal and fetal deaths worldwide.
- Preeclampsia is a complex disorder usually diagnosed after 20 weeks of pregnancy and is linked to issues in the immune system and inadequate blood flow to the placenta, causing various complications.
- Current research suggests that targeting the immune system with specific medications could provide new treatment options for preeclampsia, as the immune dysfunction plays a key role in its development.
CRISPR/Cas9 is an enabling RNA-guided technology for genome targeting and engineering. An acute DNA binding constraint of the Cas9 protein is the Protospacer Adjacent Motif (PAM). Here we demonstrate that the PAM requirement can be exploited to specifically target single-nucleotide heterozygous mutations while exerting no aberrant effects on the wild-type alleles.
View Article and Find Full Text PDFMicroRNAs (miRNAs) are a class of short noncoding RNAs which are endogenously expressed in many organisms and regulate gene expression by binding to messenger RNA (mRNA). MicroRNAs are either produced from their independent transcription units in intergenic regions or lie in intragenic regions. Intragenic miRNAs and their host mRNAs are produced from the same transcript by the microprocessor and the spliceosome protein complex respectively.
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