Publications by authors named "Negron R"

Background: Contradictory data are available on the possible association between sarcopenia and other clinical disorders in patients with chronic kidney disease (CKD) undergoing hemodialysis.

Objective: To determine the association between sarcopenia and markers associated with systemic inflammation, fasting glycemia, and quality of life in older people with CKD undergoing hemodialysis.

Methods: This was an analytical cross-sectional study.

View Article and Find Full Text PDF

Objectives: To assess the efficacy of a sustained educational intervention to affect diverse outcomes across the pregnancy and infancy timeline.

Setting: A multi-arm cluster-randomised controlled trial in 99 villages in Honduras' Copán region, involving 16 301 people in 5633 households from October 2015 to December 2019.

Participants: Residents aged 12 and older were eligible.

View Article and Find Full Text PDF

Background: Elements of charrette planning were employed to develop and examine the relationship between transnationalism, culture and health.

Objective: This paper describes the partnership, the first two stages of the planning charrette and lessons learned.

Methods: During charrette planning phase 1 we collected data through social network interviews (n = 58), cultural conversations (n = 88), and photovoice (n = 9).

View Article and Find Full Text PDF

Objective: To evaluate a single surgeon's 20-year experience with robotic radical prostatectomy.

Methods: Patients who had undergone robot-assisted laparoscopic prostatectomy by a single surgeon were identified via an IRB approved prospectively maintained prostate cancer database. Patients were divided into 5-year cohorts (cohort A 2001-2005; cohort B 2006-2010; cohort C 2011-2015; cohort D 2016-2021) for analysis.

View Article and Find Full Text PDF

Background: Individuals diagnosed with melanoma before the age of 40 years (young-onset melanoma survivors) and their first-degree relatives (FDRs) are a growing population at risk for developing recurrent melanoma or new melanomas. Regular surveillance using clinical skin examination (CSE) and skin self-examination (SSE) and engagement in preventive behaviors including sun protection are recommended. Given the growing population of survivors and their families who are at increased risk, it is surprising that no behavioral interventions have been developed and evaluated to improve risk-reduction behaviors.

View Article and Find Full Text PDF

Para comprender mejor los factores que influyen en la salud y el bienestar de los inmigrantes dominicanos, exploramos las formas en que la inmigración influye en las prácticas culturales, el comportamiento de salud y la salud. Los inmigrantes dominicanos (n = 42) participaron en cinco discusiones grupales reflexivas y no estructuradas y (n = 5) participaron en un grupo de fotovoz intergeneracional. La pérdida del contexto familiar y social en el que tradicionalmente se llevan a cabo las prácticas dietéticas dominicanas fue un tema destacado.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the correlation between ACR TI-RADS ultrasound scores and the risk of malignancy in cases with indeterminate thyroid fine needle aspiration cytology.
  • A total of 46 cases were analyzed, revealing that most indeterminate cases had higher TI-RADS scores (TR4 and TR5) and that RAS mutations were the most common molecular alteration identified.
  • The results suggest that while molecular testing is useful for TR4 and TR5 lesions, lower TI-RADS scores (TR2 and TR3) frequently showed no significant molecular changes, indicating the importance of ultrasound features in evaluating indeterminate cytology.
View Article and Find Full Text PDF

is a mobile platform created by the Human Nature Lab at the Yale Institute for Network Science to collect high-quality, location-aware, off-line/online, multi-lingual, multi-relational social network and behavior data in hard-to-reach communities. Respondents use to identify their social contacts by name and photograph, a procedure especially useful in low-literacy populations or in contexts where names may be similar or confusing. We use social network data collected from 1,969 adult respondents in two villages in Kenya to demonstrate ' ability to provide unprecedented metadata to monitor and report on the data collection process including artifactual variability based on surveyors, time of day, or location.

View Article and Find Full Text PDF

In order to better understand factors that influence the health and well-being of Dominican immigrants, we explored the ways in which immigration influences cultural practices, health behavior, and health. Dominican immigrants ( = 42) took part in five reflective and unstructured group discussions and ( = 5) participated in an intergenerational photovoice group. The loss of the familial and social context in which Dominican dietary practices traditionally take place was a salient theme.

View Article and Find Full Text PDF
Article Synopsis
  • The study analyzed changes in guidelines for reporting benign endometrial cells (BECs) in cervical cytology, specifically raising the reporting age from 40 to 45 years under the 2014 Bethesda System (TBS 2014).
  • Researchers reviewed follow-up results of Papanicolaou tests in women aged 40 and older, finding that a significant portion showed benign results, particularly in younger age groups, with notable differences observed in women aged 50 and older.
  • The findings support the justification for the TBS 2014 revision and suggest that an age threshold of 50 years may be more appropriate for reporting BECs than the current 45 years.
View Article and Find Full Text PDF

Extracardiac rhabdomyoma is an uncommon benign striated muscle tumor with a predilection for the head and neck region. However, it is extremely rare for extracardiac rhabdomyoma to present as a thyroid nodule. We report a case of rhabdomyoma diagnosed by thyroid fine-needle aspiration (FNA) in a patient with Birt-Hogg-Dubé (BHD) syndrome.

View Article and Find Full Text PDF
Article Synopsis
  • The American College of Radiology (ACR) developed the Thyroid Imaging Reporting and Data System (TI-RADS) to improve thyroid ultrasound evaluations and predict the likelihood of cancer in thyroid nodules using a scoring system from TR1 to TR5 based on various ultrasound features.* -
  • An analysis of 361 thyroid nodules with available ACR TI-RADS reports revealed that most nodules fell into the TR4 and TR3 categories, with no nodules classified as TR2 or TR3 corresponding to malignant cytology (Bethesda category VI).* -
  • The study found a correlation between TI-RADS categories and cytology results, indicating that higher TI-RADS scores (TR4 and TR5) were associated
View Article and Find Full Text PDF

We describe a sequential qualitative ➔ quantitative mixed-method procedure used to construct conceptually grounded quantitative metrics of interpersonal behavior from continuous spatiotemporal data. Metrics were developed from data collected during an experiment in which racially diverse participants interacted with self-resembling avatars at social events hosted in the virtual world Second Life. In the qualitative stage, the researchers conceptualized four distinct patterns of movement from overhead video recreations of participants interacting during the social events.

View Article and Find Full Text PDF

There is a need for diabetes prevention efforts targeting vulnerable populations. Our community-academic partnership, the East Harlem Partnership for Diabetes Prevention, conducted a randomized controlled trial to study the impact of peer led diabetes prevention workshops on weight and diabetes risk among an economically and racially diverse population in East Harlem, New York. We recruited overweight/obese adults from more than 50 community sites and conducted oral glucose tolerance testing and completed other clinical assessments and a health and lifestyle survey.

View Article and Find Full Text PDF

Evidence-based interventions (EBIs) to promote cancer control among Latinos have proliferated in recent years, though adoption and implementation of these interventions by faith-based organizations (FBOs) is limited. Capacity building may be one strategy to promote implementation. In this qualitative study, 18 community key informants were interviewed to (a) understand existing capacity for health programming among Catholic parishes, (b) characterize parishes' resource gaps and capacity-building needs implementing cancer control EBIs, and (c) elucidate strategies for delivering capacity-building assistance to parishes to facilitate implementation of EBIs.

View Article and Find Full Text PDF

Introduction: Despite global progress on many measures of child health, rates of neonatal mortality remain high in the developing world. Evidence suggests that substantial improvements can be achieved with simple, low-cost interventions within family and community settings, particularly those designed to change knowledge and behaviour at the community level. Using social network analysis to identify structurally influential community members and then targeting them for intervention shows promise for the implementation of sustainable community-wide behaviour change.

View Article and Find Full Text PDF

Stroke is a leading cause of disability in the United States and disproportionately affects minority populations. We sought to explore the quality of life in urban, minority stroke survivors through their own photos and narratives. Using the Photovoice method, seventeen stroke survivors were instructed to take pictures reflecting their experience living with and recovering from stroke.

View Article and Find Full Text PDF

Background: Variants of the APOL1 gene increase risk for kidney failure 10-fold, and are nearly exclusively found in people with African ancestry. To translate genomic discoveries into practice, we gathered information about effects and challenges incorporating genetic risk in clinical care.

Methods: An academic-community-clinical team tested 26 adults with self-reported African ancestry for APOL1 variants, conducting in-depth interviews about patients' beliefs and attitudes toward genetic testing- before, immediately, and 30 days after receiving test results.

View Article and Find Full Text PDF

People of African ancestry (Blacks) have increased risk of kidney failure due to numerous socioeconomic, environmental, and clinical factors. Two variants in the APOL1 gene are now thought to account for much of the racial disparity associated with hypertensive kidney failure in Blacks. However, this knowledge has not been translated into clinical care to help improve patient outcomes and address disparities.

View Article and Find Full Text PDF

Background And Purpose: Although poststroke depression is common, racial-ethnic disparities in depression among stroke survivors remain underexplored. Thus, we investigated the relationship between race/ethnicity and depression in a multiracial-ethnic stroke cohort.

Methods: Baseline survey data of validated scales of depression and functional status, demographics, comorbidities, and socioeconomic status were used from a recurrent stroke prevention study among community-dwelling urban stroke/transient ischemic attack survivors.

View Article and Find Full Text PDF

Introduction: In the United States, Latinos and Blacks are disproportionately affected by HIV/AIDS, but have been underrepresented in HIV vaccine trials. We assessed screening and enrollment of Blacks and Latinos for preventive HIV vaccine trials conducted in New York City, 2009-2012.

Methods: A retrospective analysis was conducted among 18-50 year old men and transgender women screening for four preventive phase 1 and 2 HIV vaccine trials.

View Article and Find Full Text PDF

The purpose of this study was to explore potential mediators of the relationship between depression and obesity in a sample of low-income, minority women. Data were extracted from a sample of 535 women enrolled in a weight loss intervention for the prevention of type 2 diabetes. Using a non-parametric bootstrapping procedure, the potential mediation effects of stress eating and sleep disturbance on the relationship between depression and obesity were tested.

View Article and Find Full Text PDF

Background: Faith-based organizations (FBOs) have been successful in delivering health promotion programs for African Americans, though few studies have been conducted among Latinos. Even fewer have focused on organizational change, which is required to sustain community-based initiatives. We hypothesized that FBOs serving Latinos would be more likely to offer evidence-based strategies (EBS) for cancer control after receiving a capacity enhancement intervention to implement health programs, and designed the CRUZA trial to test this hypothesis.

View Article and Find Full Text PDF

Background: We describe activities undertaken to conduct organizational surveys among faith-based organizations in Massachusetts as part of a larger study designed to promote parish-based cancer control programs for Latinos.

Method: Catholic parishes located in Massachusetts that provided Spanish-language mass were eligible for study participation. Parishes were identified through diocesan records and online directories.

View Article and Find Full Text PDF