Publications by authors named "Negrini S"

The growing relevance of rehabilitation in healthcare to address increasing patient needs necessitates robust Physical and Rehabilitation Medicine (PRM) integration into medical education and practice. Academic PRM, rooted in medical faculties, is vital for developing the medical speciality as an academic discipline across Europe, where it faces challenges, including limited representation in medical schools and competition for resources with established disciplines. This commentary advocates establishing a representative organization for academic PRM in Europe.

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: The aim of our study was to verify whether the application of Kinesiotaping in addition to the usual treatment was superior to the usual treatment alone regarding functional outcome, pain, and edema in the first 13 days after total knee arthroplasty (TKA) surgery. : The study sample ( = 71) comprised 42.3% men and the mean age was 68.

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  • A study in Piedmont, Italy evaluated the impact of an Allergy Call Center (ACC) program established to support patients at high risk for allergic reactions during the COVID-19 vaccination campaign.
  • The ACC operated from May 2021 to December 2022, receiving 15,865 calls, with only 336 patients needing further referral to the specialized unit, indicating effective management of consultations.
  • Overall, the study highlighted the success of proactive screening in reducing allergy-related concerns linked to COVID-19 vaccination, streamlining the referral process for high-risk patients.
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Despite recognized need and reasonable demand, health systems and rehabilitation communities keep working in silos, independently with minimal recognition to the issues of those who require rehabilitation services. Consolidated effort by health systems and rehabilitation parties, recognizing the value, power and promise of each other, is a need of the hour to address this growing issue of public health importance. In this paper, the importance and the need for integration of rehabilitation into health system is emphasized.

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  • * Single-case experimental designs (SCEDs), such as N-of-1 RCTs, are gaining popularity as they allow for causal inference in small participant groups and provide each participant as their own control.
  • * The manuscript highlights how SCEDs can effectively answer clinical rehabilitation questions by enhancing internal validity, improving user acceptance among clinicians and participants, and expanding evidence where RCTs are less feasible.
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We report the first, to our knowledge, observation of the nonlinear phenomenon known as modulation instability (MI) in a coherently driven fiber resonator pumped at 1972 nm. To compensate for the very high losses in this spectral region, we have integrated a thulium-doped fiber amplifier inside the cavity. Lower losses allow a lower MI threshold, leading to the observation of this phenomenon at a moderate input power.

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Purpose: Understanding idiopathic scoliosis (IS) natural history during growth is essential for shared decision-making between patients and physicians. We developed a retrospective model with the largest available sample in the literature and we aimed to investigate if using three peri-pubertal growth periods provides better prediction than a unique model.

Methods: Secondary analysis of a previous study on IS natural history data from radiographs before and at the first consult.

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Background: Different studies report that systemic lupus erythematosus (SLE) tends to have a more aggressive course in Hispanic patients. In this study, we analysed epidemiologic, clinical, and laboratory characteristics in a cohort of Hispanic and Caucasian lupus patients in the context of Italian health service, which provides free access to care to all citizens, thus mitigating the impact of socioeconomic factors that negatively influence the course of the disease in ethnic minorities.

Methods: This single-center retrospective study was conducted at the San Martino Hospital "Lupus Clinic" in Genoa, Italy.

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This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of assistive technologies (i.e.

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According to Cochrane Rehabilitation's recently published definition for research purposes, rehabilitation is inherently complex. Rehabilitation teams frequently implement multiple strategies concurrently, draw on input from a range of different health professionals, target multiple outcomes, and personalize therapeutic plans. The success of rehabilitation lies not only in the specific therapies employed, but also in how they are delivered, when they are delivered, and the capability and willingness of patients to engage in them.

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: The Sforzesco brace is a very rigid push-up brace effective in adolescent idiopathic scoliosis (AIS). We recently developed a new Sforzesco brace based on modularity (the Modular Italian brace-MI brace) that could allow standardization, facilitating global expertise diffusion, increased modifiability and adaptability, and cost savings due to longer brace life. We aimed to compare the short-term results of the two braces.

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  • * Recent research indicates that the connection between anti-dsDNA antibodies and kidney problems is weak, and it showcases a variety of other renal-targeting autoantibodies, including increased attention to the IgG2 isotype, which was previously overlooked.
  • * New "second wave antibodies" have emerged, which play a role in modulating inflammation in the kidneys, suggesting they could be key in refining treatment strategies and monitoring therapeutic responses in LN patients.
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. This overview of Cochrane systematic reviews (CSRs) reports on current evidence on the effectiveness of rehabilitation interventions for persons with upper limb fractures (ULFs), and the quality of the evidence. .

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Introduction: The evidence on the utility and effectiveness of rehabilitation interventions delivered via telerehabilitation is growing rapidly. Telerehabilitation is expected to have a key role in rehabilitation in the future.

Aim: The aim of this evidence-based position paper (EBPP) is to improve PRM physicians' professional practice in telerehabilitation to be delivered to improve functioning and to reduce activity limitations and/or participation restrictions in individuals with a variety of disabling health conditions.

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This article was published in volume 58, issue 6 of publishing year 2022, with a mistake in Table II. The correct Table II is the one included in this erratum.

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Rehabilitation providers and policymakers need valid evidence to make informed decisions about the healthcare needs of the population. Whenever possible, these decisions should be informed by randomized controlled trials (RCTs). However, there are circumstances when evidence needs to be generated rapidly, or when RCTs are not ethical or feasible.

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Background: Adolescent idiopathic scoliosis (AIS) is a pathology that changes the three-dimensional shape of the spine and trunk. While AIS can progress during growth and cause cosmetic issues, it is usually asymptomatic. However, a final spinal curvature above the critical threshold of 30° increases the risk of health problems and curve progression in adulthood.

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  • Research in health policy, systems, and services (HPSSR) has gained traction in rehabilitation, driven by the need to tackle complex healthcare challenges effectively.
  • The World Health Assembly's resolution emphasizes promoting high-quality rehabilitation research and outlines various HPSSR study designs at macro, meso, and micro levels.
  • The paper categorizes research questions, provides examples of methodologies, and highlights the importance of implementing findings in clinical practice to improve healthcare delivery and patient outcomes.
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Adolescent idiopathic scoliosis (AIS) is a three-dimensional spine and trunk deformity. Bracing is an effective treatment for medium-degree curves. Thermal sensors help monitor patients' adherence (compliance), a critical issue in bracing treatment.

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Introduction: Systemic sclerosis (SSc) affects the connective tissue and leads to an abnormal fibrotic process in the skin and internal organs. Epidermal Growth Factor Receptor (EGFR) is able to induce cell proliferation and differentiation, and its expression is increased in SSc patients with pulmonary artery hypertension and in skin biopsies in patients with scleroderma. To date, no data on esophageal expression of EGFR are available in SSc patients.

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The paper introduces the Special Sections of the European Journal of Physical and Rehabilitation Medicine dedicated to the 5 Methodological Meeting of Cochrane Rehabilitation. It introduces Cochrane Rehabilitation; its vision, mission and goals; discusses why the Methodological Meetings were created; and reports on their organisation and previous outcomes. The core content of this editorial is the 5 Methodological Meeting held in Milan in September 2023.

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