A fluorescence imaging-supported aptasensor for sensitive monitoring of cadmium pollutant in diverse samples: A critical role of metal organic frameworks.

Water pollution, as the remarkable environmental remediation issue, is a today worldwide concern. Cadmium ion (Cd) as a hazardous water pollutant is seriously detrimental to human health, food safety, and ecological areas. Hence, we successfully designed a simple detection array for monitoring of ultra-low levels of Cd ion by combining the advantages of aptamer as a high sensitive and selective sensing probe and zeolitic imidazolate framework-8 (ZIF-8) as a superior fluorescence quenching inducer.

Metal organic frameworks as advanced functional materials for aptasensor design.

Background: Advancement in coordination chemistry has achieved an impressive development of metal organic frameworks (MOFs) as the supramolecular hybrid materials, comprising harmonized metal nodes with organic ligands. Scope and approach: MOFs offer the unique properties of easy synthesis, nanoscale structure, adjustable size and morphology, high porosity, large surface area, supreme chemical tunability and stability, and biocompatibility. The features provide an exceptional opportunity for the widely usage of MOFs in the different scientific fields, e.

A simple and ultrasensitive metal-organic framework-based aptasensor for fluorescence detection of ethanolamine.

In this research, a facile fluorescence aptasensor was designed for the ultrasensitive determination of ethanolamine (ETA) as an aliphatic amino alcohol molecule with harmful side effects for human health. Zeolitic imidazolate framework-8 (ZIF-8) as an efficient metal-organic framework was applied to quench the fluorescence emission of the FAM-labeled ETA aptamer. The presence of ETA could recover the fluorescence response under the optimal experimental conditions.