World J Pediatr Congenit Heart Surg
December 2024
We present a case study of neotricuspidization of the aortic valve with neocusp suturing based on templates similar to those used in the Ozaki procedure but adapted for infants. This is an alternative for patients when valve reconstruction is impossible or risky. A good postoperative hemodynamic outcome was obtained, but it is necessary to evaluate this approach on the basis of long-term results.
View Article and Find Full Text PDFUnlabelled: Excessive postoperative scarring halts the effectiveness of glaucoma surgery and still remains a challenging problem. The purpose of this study was to develop a PLA-PEG-based drug delivery system with cyclosporine A or everolimus for wound healing modulation.
Methods: PLA-PEG implants saturation with cyclosporine A or everolimus as well as their further in vitro release were analyzed.
Coupling to longitudinal modes of thin spherical shells, under Gaussian-beam illumination, was explored with a theoretical method based on Fourier-optics analysis and vector spherical harmonics and was scrutinized with an experimental setup. For the theory part, the illumination frequency band was fixed between 100-600 GHz and the outer spherical shell radius of curvature and thickness are 7.5 mm and 0.
View Article and Find Full Text PDFImproving the longitudinal modes coupling in layered spherical structure contributes significantly to corneal terahertz sensing, which plays a crucial role in the early diagnosis of cornea dystrophies. Using a steel sphere to calibrate reflection from the cornea sample assists in enhancing the resolution of longitudinal modes. The requirement and challenges toward applying the calibration sphere are introduced and addressed.
View Article and Find Full Text PDFThin layers of silver nanowires are commonly studied for transparent electronics. However, reports of their terahertz (THz) properties are scarce. Here, we present the electrical and optical properties of thin silver nanowire layers with increasing densities at THz frequencies.
View Article and Find Full Text PDFReduction of terbium(III) double-decker phthalocyanine, TbPc (1), by sodium fluorenone ketyl in the presence of bis(triphenylphosphoranylidene)ammonium cations yields one-electron-reduced (PPN){Tb(Pc)}·2.5CHCl (2) containing the dianionic Pc macrocycles, whereas a stronger NaCpCo(CO) reductant in the presence of an excess of cryptand yields two-electron-reduced {Cryptand(Na)}{(Pc)Tb(Pc)} (3) containing the Pc radical trianionic macrocycle. Isolated pairs of the {Tb(Pc)} anions are formed in 2, whereas compound 3 has unique 3D packing of the macrocycles with weak π-orbitals overlapping in all three directions.
View Article and Find Full Text PDFThe goal of the research was to elaborate a model for prognosticating the probability of the development of long-term coronogenic complications after the arterial switch operation. A single-center retrospective cohort study of the outcomes of treating 248 patients with TGA has been conducted. All the patients underwent an AS operation at the clinic of Bakulev National Medical Research Center of Cardiovascular Surgery.
View Article and Find Full Text PDFAviakosm Ekolog Med
April 2018
The effect of long-duration space flight on the vital processes in human chondroblasts in vitro was studied with a number of morphologic, biochemical and optic techniques. Object of investigation was a 3-D porous biocarrier populated by a cell culture in a leak-free vessel completely full of growth medium. The investigation was performed onboard automatic .
View Article and Find Full Text PDFThe apparent tendency of decreasing male fertility is observed during last years. Basically, this occurrence is related to deterioration of environment conditions, harmful habits and male's organism state. The WHO standards of indicators of spermogram were formulated by averaging the statistical data collected in various countries.
View Article and Find Full Text PDFAim: To elucidate association of a polymorphic marker C825T of the beta(3)-subunit of G-protein with myocardial hypertrophy in hypertension.
Material And Methods: Alleles of polymorphic marker C825T of the CNB3 gene were identified by polymerase chain reaction with subsequent cleavage of the product by BseDI restrictase in 135 patients with hypertensive disease (essential hypertension). Left ventricular mass was determined by echocardiography.
The total gamma-irradiation of Wistar rats at a dose of 0.25 Gy as well as at higher doses (0.5, 2 and 4.
View Article and Find Full Text PDFExamination of 2563 offsprings of Wistar rats after irradiation of one or both parents with doses of 0.25, 0.5, 1, 2, 3 and 4 Gy was carried out; the manifestation of lethal effects in the progeny of the first generation in ontogenesis was studied.
View Article and Find Full Text PDFRadiats Biol Radioecol
November 2000
The problem of hereditary effects of mammal exposure to ionizing radiation has a 95-year history but to date, no simple final solution has been available. Many papers on this problem specify the dependence of the hereditary effects on dose rate, regime, physical nature of radiation exposure, type, line and age of mammals that were studied. Over many years it was studied mainly as an aspect of hereditary radiation effects in progeny of one irradiated and the second non-irradiated parents.
View Article and Find Full Text PDFThe paper outlines the computer-aided testing diagnostic systems used at the Moscow Therapeutical Research Center for Prevention and Treatment of Mental and Nervous Disability. They are based on the complex factorial approach. This approach takes into account the developmental vectors in a child.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
December 1998
The paper reports the case of sibs, brother and sister, with Martin-Bell's syndrome confirmed cytogenetically. Mental retardation and autism were the main phenomena in the clinical picture. Positive effect was achieved by means of Skvortsov--Osipenko method (metameric injection of cerebral hydrolysates' preparations, stimulation of visual, acoustic and proprioceptive analyzers).
View Article and Find Full Text PDFAim: To evaluate the haemopoietic function of bone marrow blood forming cells in human myelodysplastic syndromes (MDS) by silver staining of nucleolar organiser regions (AgNORs).
Methods: Nucleoli were investigated in bone marrow blast cells and in erythroid, granulocytic, and megakaryocytic cells from 12 haematologically healthy subjects, and from 26 patients with MDS, including 14 with refractory anaemia (RA), nine with RA with excess blasts (RAEB), and three with RAEB in transformation (RAEB-t). The investigation was performed before treatment using a one step silver staining method.
The paper summarises some methodological approaches which may be used in experimental modelling and study of hereditary radiation effects in mammals. These approaches are aimed to the elucidation of the possible specific character (aggravation) of radiation damage in the offspring determined by the participation of two exposed parents in conception. The main attention is drawn to the dependence of hereditary radiation effects yield on the stages of the cell cycle of the parent germ cells at the moment of exposure and to criteria of evaluation of radiation damage in the offspring during the ontogenetic development.
View Article and Find Full Text PDFData on long-term interferon-alpha (reaferon) therapy in 6 patients with CML (5 in chronic phase, 1 in acceleration phase) are presented. Clinicohematological remission was achieved in all the patients in a chronic phase irrespective of their group of risk. Cytogenetic improvement occurred only in one patient from a low-risk group.
View Article and Find Full Text PDFIn experiments with Wistar rats it was shown that the efficiency of mexamine as radioprotector was substantially lower when sex cells of both parents (spermatozoids, spermatids, ovocytes) were irradiated with a dose of 2-4 Gy than after irradiation one parent only. It may be associated with the aggravation of effects in the posterity being conceived from gametes of both exposed parents.
View Article and Find Full Text PDFRadiats Biol Radioecol
November 1995
Acute gamma-irradiation with a dose of 4 Gy of germinal cells of both parents in postmeiotic stages of gametogenesis results in increase of ineffective copulation rate. Antenatal and postnatal ontogenesis of first generation progeny shows worse consequences as compared with only one parent germinal cell irradiation.
View Article and Find Full Text PDFExamination of 15 patients with clofelin poisoning cleared up clinical symptoms of the condition. The impairment was chiefly inflicted to cardiovascular system and neuropsychic status. There appeared arterial hypotonia, long-term orthostatic hypotonia combined with bradycardia and extrasystolic arrhythmia.
View Article and Find Full Text PDFHPLC of the beef heart cytochrome oxidase subunits on TSKgel-column has been studied. It was found that the resolution of the subunits depends on the sodium dodecyl sulphate and buffer concentration. Strong interaction of subunits Va, VIc and VIIb with hydrophobic polypeptide chains was observed.
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