Background: There is accumulating evidence of the presence of Cancer Stem Cells (CSCs) within meningiomas (MGs). In the present study, we assessed the Immunohistochemistry (IHC) expression of stem cell markers SOX2, OCT4, CD133 in different grades of MGs and their correlation with Ki 67 index.
Methods: A cross-sectional analytical study where 140 MGs cases were graded and classified according to WHO-2021 classification.
Mesenchymal tumors arising in the penis are extremely uncommon. Sarcomas must be distinguished from sarcomatoid squamous carcinomas, owing to their treatment and prognostic implications. We report a rare case of leiomyosarcoma of the penis in a 70-year-old patient.
View Article and Find Full Text PDFMed J Armed Forces India
April 2022
Background: Rubella, although a fairly innocuous disease, is a known cause of severe birth defects in newborn. With number of women in uniform on the rise and they being assigned instructional and medical care duties, adult rubella outbreak in a training centre as in this study poses grave threat to them; besides, having disruption potential for their training.
Methods: This study was conducted at an Airmen Training Centre of the Indian Air Force having more than 2500 recruits, in five squadrons.
Indian J Pathol Microbiol
February 2022
Introduction: Synovium has been documented as a primary site of inflammation and a major effector organ in a variety of joint diseases. Study of simple technique like synovial biopsy can help in early diagnosis and treatment of diseases significantly improving outcome of patient in cases of rheumatoid arthritis, osteoarthritis, etc., Only limited data exist on utility of synovial biopsies.
View Article and Find Full Text PDFBackground: Management of novel viral respiratory disease outbreak on-board a ship with person-to-person transmission can be a public health challenge because of close proximity of inhabitants due to confined space and air-conditioned environment. It has a potential to be explosive, with high secondary attack rate (SAR) and cause significant morbidity and mortality. This study compares control measures instituted on-board two ships with similar outbreaks and recommends a standardized evidence-based outbreak response against them.
View Article and Find Full Text PDFEctopic cervical thymus is a rare congenital anomaly, which results because of the failure of complete descent of the thymus. They are incidental findings in the young and may disappear during the early years of life; however, they have rarely been described in adults. Some of them may undergo hyperplasia or neoplastic transformation and become visible or cause symptoms.
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