Magnetic resonance quantitative myocardial perfusion reserve demonstrates improved myocardial blood flow after angiogenic implant therapy.

Purpose: The purpose of this study is to follow myocardial angiogenesis temporally using quantitative magnetic resonance first pass perfusion imaging and compare this with the "gold standard" of radioactive microspheres in a random subset of animals.

Materials And Methods: Ameriod constrictors were placed around the left circumflex in 15 pigs to induce an ischemic area. Two groups were randomized to receive either a sham operation or treatment with angiogenic implants inserted into myocardium in the distribution of the left circumflex artery (LCX).

Utility of cardiac magnetic resonance imaging in the diagnosis of hypertrophic cardiomyopathy.

Background: Two-dimensional echocardiography is currently the standard test for the clinical diagnosis of hypertrophic cardiomyopathy (HCM). The present study was undertaken to determine whether cardiac MRI (CMR) affords greater accuracy than echocardiography in establishing the diagnosis and assessing the magnitude of left ventricular (LV) hypertrophy in HCM.

Methods And Results: Forty-eight patients (age 34+/-16 years) suspected of having HCM (or with a confirmed diagnosis) were imaged by both echocardiography and CMR to assess LV wall thickness in 8 anatomic segments (total n=384 segments) and compared in a blinded fashion.

Multiple plaque morphologies in a single coronary artery: insights from volumetric intravascular ultrasound.

Intravascular ultrasound provides detailed information on vessel wall and plaque morphology. This report illustrates the use of three-dimensional volumetric IVUS reconstruction images to characterize different patterns of plaque morphology, including vulnerable and ruptured plaques, within a single coronary artery in a patient with unstable angina.