Study of multimodal light emissions from Pr/Yb doped NaLa(MoO) phosphors for optoelectronic devices and plant-growth applications.

Recent advancements in materials design have driven the scientific community to explore phosphor materials for multifunctional applications. This study presents the multimodal light emission (downshifting - DS, quantum cutting - QC, and upconversion - UC) from Pr/Yb activated NaLa(MoO) phosphors for multifunctional applications. Under blue (449 nm) and NIR (980 nm) excitation, co-doped phosphors emit visible light through DS and UC processes caused by different f-f transitions of Pr ions.

Spectroscopic insights with molecular docking and molecular dynamic simulation studies of anticancer drug 5-Fluorouracil targeting human pyruvate kinase m2.

This study was conducted to test the efficacy of 5-fluorouracil (5-FU) as an anticancer drug against the human pyruvate kinase isozyme M2 (PKM2) using spectroscopic, molecular docking and molecular dynamic simulation studies. PKM2 fluorescence quenching studies in the presence of 5-FU performed at three different temperatures indicates dynamic quenching processes with single-set of binding ( ≈ 1) profile. The biomolecular quenching constants () and the effective binding constants () obtained are shown to increase with temperature.

Upconversion luminescence based temperature sensing properties and anti-counterfeiting applications of GdNbO:Tm/Yb phosphor.

Pure monoclinic phase GdNbO:Tm/Yb phosphor was prepared using solid state reaction method for upconversion emission, optical thermometry, latent fingerprints visualization and anti-counterfeiting applications. The prepared phosphor exhibits colour tunability with temperature variation (from blue to almost white) and good suppression of thermal quenching. The temperature sensing characteristic from thermally and non-thermally coupled levels of Tm ion were investigated using the fluorescence intensity ratio (FIR) approach.

Catalyst-Controlled C-H Allylation and Annulation of 2-Aryl Quinazolinones with 2-Methylidene Cyclic Carbonate.

The site-selective modification of quinazolinone as a privileged bicyclic N-heterocycle is an attractive topic in medicinal chemistry and material science. We herein report the ruthenium(II)-catalyzed C-H allylation of 2-aryl quinazolinones with 2-methylidene cyclic carbonate. In addition, tandem C-H allylation and annulation are achieved under rhodium(III) catalysis, resulting in the formation of tetracyclic quinazolinones including a tertiary carbon center.

Strategy to probe multimodal light emissions from Eu/Yb activated garnet nanophosphors for LED devices and solar cell applications.

This study investigates multimodal light emission from an Eu/Yb activated YGaO (YGG) nanophosphor synthesized using a low temperature solution combustion method. The prepared sample possesses a cubic phase and an 3̄ space group and this is confirmed with X-ray diffraction and Rietveld refinement analysis. The synthesized sample shows orange-red emission bands because of the f-f transitions of Eu under UV (393 nm) and NIR (980 nm) excitations downshifting (DS) and upconversion (UC) processes, respectively.

Probing multimodal light emission from Tb/Yb-doped garnet nanophosphors for lighting applications.

Herein we report the solution-combustion-method-synthesized Tb- and Tb/Yb-doped GdGaO nanophosphors, which possess luminescent and magnetic properties. The phase formation/crystal structure, and morphology of the prepared nanophosphors are studied using X-ray diffraction (XRD)/Raman spectroscopy and a field emission scanning electron microscope (FE-SEM), respectively. Tb/Yb-doped phosphor samples exhibit green emission with an intense band around 544 nm through downshifting (DS) and upconversion (UC) processes because of the D → F transition of Tb.

Light-induced dissolution and concomitant crystallization of a Keggin-type polyoxometalate mimicking a naturally occurring phenomenon.

A suspension of a yellow polycrystalline compound [PPh][PMoO] in -methylformanilide (NMF) (in which it is not soluble), on irradiation with sunlight, initiates dissolution its reduction followed by its crystallization leading to the isolation of single crystals of compound [PPh][PMoMoO]·3CH(CH)NCHO (1). Compounds [PPh][PMoO]·1.75 CH(CH)NCHO (2) and [PPh][PMoO]·2CH(CH)NCHO (3), each containing an oxidized Keggin anion, are obtained at two different temperatures when the corresponding mother liquor is kept in the dark.

Structural and Functional Characterization of Homoserine Transacetylase.

() lacking functional homoserine transacetylase (HTA) is compromised in methionine biosynthesis, protein synthesis, and in the activity of multiple essential -adenosyl-l-methionine-dependent enzymes. Additionally, deficient mutants are further disarmed by the toxic accumulation of lysine due to a redirection of the metabolic flux toward the lysine biosynthetic pathway. Studies with deletion mutants and crystallographic studies of the apoenzyme have, respectively, validated HTA as an essential enzyme and revealed a ligandable binding site.

Rhodium(III)-Catalyzed Conjugate Addition of β-CF-Enones with Quinoline -Oxides.

The site-selective incorporation of a trifluoromethyl group into biologically active molecules and pharmaceuticals has emerged as a central topic in medicinal chemistry and drug discovery. Herein, we demonstrate the rhodium(III)-catalyzed conjugate addition of β-trifluoromethylated enones with quinoline -oxides, which result in the generation of β-trifluoromethyl-β'-quinolinated ketones. The reaction proceeds under mild conditions with complete functional group tolerance.

Perovskite LaKCoO (0 ≤ ≤ 0.5): a novel bifunctional OER/ORR electrocatalyst and supercapacitive charge storage electrode in a neutral NaSO electrolyte.

The as-prepared LaKCoO (0 ≤ ≤ 0.5) showed superior pseudocapacitive charge storage capacity in a neutral 0.5 M NaSO electrolyte and superior electrocatalytic activities for the oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) in a 1 M KOH electrolyte.

Methylene Thiazolidinediones as Alkylation Reagents in Catalytic C-H Functionalization: Rapid Access to Glitazones.

The straightforward and rapid incorporation of a thiazolidinedione scaffold into prefunctionalized (hetero)aromatic compounds is in demand for the development of antidiabetic glitazones and other pharmaceuticals. Herein, we report the unprecedented N- and O-directed C-H alkylation of various (hetero)arenes with methylene thiazolidinediones under rhodium(III) catalysis. The applicability of the developed protocol in challenging contexts is exhibited by the late-stage installation of a methylene thiazolidinedione moiety on the C-H bond of commercially available drug molecules.

Comparative study of upconversion and photoacoustic measurements of Er/Ybdoped LaOphosphor under 980 nm.

The Er/Ybdoped LaOphosphor samples were synthesized by the combustion method and then photoluminescence and photoacoustic spectroscopic studies were done. Prepared samples were annealed at 800 °C, 1000 °C and 1300 °C and all samples were found in pure hexagonal phase as confirmed by XRD analysis. From FE-SEM images it is found that particle size increases with increase in annealing temperature.

C-H amidation of 2-aryl azlactones under iridium(III) catalysis: access to chiral amino acids.

In this study, we examine the site-selctive iridium(III)-catalyzed C-H amidation between 2-aryl azlactones and acyl azides. This transformation produces a range of -amidated azlactones, which act as precursors for the synthesis of chiral amino acids organocatalyzed ring-opening reactions. To test its effectiveness, the method developed is applied to the late-stage C-H amidation of complex drug molecules.

Ruthenium(II)-Catalyzed Tandem C-H Allylation and [3 + 2] Dipolar Cycloaddition to Construct Bridged Tetracycles.

The ruthenium(II)-catalyzed tandem C-H allylation and intramolecular dipolar cycloaddition between azomethine imines and 2-methylidenetrimethylene carbonate is described herein. The initially formed β-substituted allyl fragment could trigger the exotype [3 + 2] cycloaddition with the polar azomethine group, resulting in the formation of bridged tetracycles bearing a hydroxymethylene group at a bridgehead carbon center. A wide substrate scope and broad functional group compatibility were observed.

Polyoxometalate-Supported Copper(I)-Pyrazole Complex: Unusual Stability, Geometrical Isomers, Organic Transformation, and Computation.

We have described the synthesis and characterization of a polyoxometalate (POM)-supported copper(I)-pyrazole complex, [Cu(CHN)] [PWO{Cu(CHN)}]·CHOH (). There are three Cu(I)-pyrazole coordination complexes in compound , out of which two are supported by the {PWO} Keggin POM by coordinate covalent bonds from the POM surface through oxygen donors to the Cu(I) centers of two Cu(I) complexes and one remains uncoordinated to the POM surface, acting as a cationic complex species in the crystals of . The POM-coordinated Cu(I) complexes have a T-shaped geometry, and the uncoordinated Cu(I) complex is a linear one.

Polymer-Induced Emission-Active Fluorine-Embedded Carbon Dots for the Preparation of Warm WLEDs with a High Color Rendering Index.

Exploration of many strategies has continuously contributed to producing aggregation-induced red-emissive carbon dots (CDs). In this work, we designed fluorine-embedded (F-embedded) CDs from 1,2,4-triaminobenzene, thiourea, and ammonium fluoride (NHF) exhibiting polymer-induced emission (PIE). The PIE phenomenon of fluorescent CDs is obtained in poly(vinyl alcohol) (PVA), showing emissions at 611 and 617 nm in the dispersed and solid states, respectively.

Cephem-Pyrazinoic Acid Conjugates: Circumventing Resistance in Mycobacterium tuberculosis.

Tuberculosis (TB) is a leading source of infectious disease mortality globally. Antibiotic-resistant strains comprise an estimated 10 % of new TB cases and present an urgent need for novel therapeutics. β-lactam antibiotics have traditionally been ineffective against M.

KOBu-promoted C3-homocoupling of quinoxalinones through single electron transfer from an sp carbanion intermediate.

The C3-selective homodimerization of quinoxalinones is described. A C3-sp carbanion species generated through deprotonation of quinoxalinone using potassium -butoxide (KOBu) transfers an electron (single electron transfer mechanism) to a second quinoxalinone, affording a radical-anion intermediate. The radical scavenging and electron paramagnetic resonance (EPR) experiments support the plausible radical reaction pathway.

Synthesis of Succinimide-Linked Indazol-3-ols Derived from Maleimides under Rh(III) Catalysis.

The structural modification of -aryl indazolols as tautomers of -aryl indazolones has been established as a hot topic in pharmaceutics and medicinal chemistry. We herein disclose the rhodium(III)-catalyzed 1,4-addition reaction of maleimides with -aryl indazol-3-ols, which provides the succinimide-bearing indazol-3-ol scaffolds with complete regioselectivity and a good functional group tolerance. Notably, the versatility of this protocol is demonstrated by the use of drug-molecule-linked and fluorescence-probe-linked maleimides.

Synthesis, characterizations and electrochemical performances of anhydrous CoCO nanorods for pseudocapacitive energy storage applications.

To overcome the environmental challenges caused by utilization of fossil fuel based energy technologies and to utilize the full potential of renewable energy sources such as solar, wind and tidal, high power and high energy density containing large scale electrochemical energy storage devices are a matter of concern and a need of the hour. Pseudocapacitors with accessibility to multiple oxidation states for redox charge transfer can achieve a higher degree of energy storage density compared to electric double layer capacitors (EDLC) and the hybrid supercapacitor is one of the prominent electrochemical capacitors that can resolve the low energy density issues associated with EDLCs. Due to its open pore framework structure with superior structural stability and accessibility of Co redox states, porous anhydrous CoCO nanorods are envisaged here as a potential energy storage electrode in a pseudo-capacitive mode.

NASICON-structured NaFePO(SO): a potential cathode material for rechargeable sodium-ion batteries.

The cost-effective and abundant availability of sodium offers an opportunity for rechargeable Na-ion batteries as an ideal replacement for rechargeable Li-ion batteries. However, the larger size and strong Na-Na interaction create multidimensional phase instability and transformation problems, especially in layer-structured NaMO (Mn, Co, Fe, and Ni) that inhibit the direct transformation of rechargeable Li-ion battery technology to Na-ion batteries. However, framework structures offer superior structural stability due to the interconnection of polyanions or polyhedra forming cationic octahedra.

Synthesis, Characterizations, and Electrochemical Performances of Highly Porous, Anhydrous CoNiCO for Pseudocapacitive Energy Storage Applications.

Electrochemical energy storage relies essentially on the development of innovative electrode materials with enhanced kinetics of ion transport. Pseudocapacitors are excellent candidates to bridge the performance gap between supercapacitors and batteries. Highly porous, anhydrous NiCoCO is envisaged here as a potential electrode for pseudocapacitor applications, mainly because of its open pore framework structure, which poses inherent structural stability due to the presence of planar oxalate anions (CO ), and active participation of Ni and Co results in high intercalative charge storage capacity in the aqueous KOH electrolyte.

Novel anti-adipogenic effect of CF-allylated indole in 3T3-L1 cells.

Indole derivatives from various plants are known to have health benefits because of their anti-cancer, anti-oxidant, anti-inflammatory, and anti-tubercular effects. However, their effects on adipogenesis have not been fully elucidated yet. Herein, we show that a newly synthesized indole derivative, CF-allylated indole, [(E)-1-(pyrimidin- 2-yl)-2-(4,4,4- trifluorobut-2-enyl)-1H-indole], effectively inhibits adipogenesis.

La K FeO: An Anion Intercalative Pseudocapacitive Electrode for Supercapacitor Application.

The green energy alternative to a fossil fuel-based economy can be provided only by coupling renewable energy solution solutions such as solar or wind energy plants with large-scale electrochemical energy storage devices. Enabling high-energy storage coupled with high-power delivery can be envisaged though high-capacitive pseudocapacitor electrodes. A pseudocapacitor electrode with multiple oxidation state accessibility can enable more than 1 charge/transfer per molecule to facilitate superior energy storage.