Publications by authors named "Neena Kenton Pyzocha"
Proc Natl Acad Sci U S A
November 2011
Article Synopsis
- The study introduces a new culture system for human pluripotent stem cells that eliminates the need for a feeder layer by modifying standard cell culture plastics with UV/ozone radiation.
- By optimizing the chemical and geometric properties of these surfaces, the researchers successfully enhance cell aggregation and significantly boost cell growth compared to traditional feeder-based cultures.
- This innovative xeno-free substrate not only increases cell yield but also supports advanced techniques like reprogramming and gene targeting, making it ideal for clinical applications and standardized disease modeling.
