Publications by authors named "Neema Kulkarni"
Objective: To examine at one-year follow-up the efficacy of an internet-based intervention for infant and toddler sleep disturbances, as well as to assess any indirect benefits to maternal sleep and confidence.
Methods: Participants included 171 (64.8%) of 264 mothers of an infant or toddler (ages 18-48 months) who had previously participated in a 3-week study.
Article Synopsis
- About 20% to 30% of young children experience sleep problems, and internet-based interventions could help make effective treatments more accessible without needing in-person professional support.
- A study involved 264 mothers and their infants/toddlers, who were divided into groups to assess the effectiveness of different Internet-based sleep interventions over three weeks.
- Results indicated that both interventions significantly improved children's sleep issues and also positively impacted mothers’ sleep, mood, and confidence in managing their child's sleep problems.
Proteins with the double stranded beta-helix (DSBH, also known as cupin) fold perform a diverse range of functions. In this study, Bacillus subtilis quercetinase was used as a model system to understand the conformational determinants of functional diversity within the cupin fold. Controlled proteolysis experiments revealed that this enzyme is active, thermo-stable and maintains its quaternary arrangement even after substantial (ca 33 %) cleavage of the protein.
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